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What Are The Benefits of Hyaluronic Acid?

Views: 0     Author: Site Editor     Publish Time: 2022-09-02      Origin: Site

1. What is hyaluronic acid?


Hyaluronic acid, also known as hyaluronic acid, hyal-means glass-like, bright and transparent, while uronic acid refers to uronic acid, which has nothing to do with uric acid.

The molecular formula is (CHNO)ₙ, which is a disaccharide unit glycosaminoglycan composed of D-glucuronic acid and N-acetylglucosamine.


The main component hyaluronic acid is an acidic mucopolysaccharide. Hyaluronic acid shows a variety of important physiological functions in the body with its unique molecular structure and physicochemical properties.


Such as lubricating joints, regulating the permeability of blood vessel walls, regulating protein, water and electrolyte diffusion and operation, and promoting wound healing.

Hyaluronic acid is a natural substance found in the fluids of the eyes and joints. It acts as a cushion and lubricant in joints and other tissues.


2. What are the uses of hyaluronic acid?


Hyaluronic acid is known for its benefits to the skin, especially relieving dry skin, reducing the appearance of fine lines and wrinkles, and accelerating wound healing.

It can also help relieve joint pain in people with osteoarthritis.


It helps things run smoothly: Hyaluronic acid helps your joints work like well-oiled machines. It prevents pain and injury from bones rubbing against each other.


It helps retain moisture: Hyaluronic acid is very good at retaining water. A quarter teaspoon of hyaluronic acid contains about a gallon and a half of water. This is why hyaluronic acid is often used to treat dry eyes. It is also used in moisturizers, lotions, ointments and serums.


It makes your skin elastic: Hyaluronic acid helps the skin stretch and flex, reducing skin wrinkles and fine lines. Hyaluronic acid has also been shown to help wounds heal faster and reduce scarring.


Hyaluronic acid originally exists in the skin, which can help the skin absorb water from the body and the surface of the skin, and can also enhance the skin's long-term water retention capacity.

When hyaluronic acid absorbs water, it makes elastic fibers and collagen in a moist environment, so the skin has elasticity.


3. How is hyaluronic acid made? What certificates do we have?


1. Animal tissue: the main raw materials are cockscomb and bull's eye vitreous.


Degreasing and dehydrating the raw materials with acetone or ethanol, soaking in distilled water, filtering, then treating with sodium chloride aqueous solution and chloroform solution, then adding trypsin to keep warm to obtain a mixed solution, and finally treating and purifying with an ion exchanger to obtain a refined transparent acid.

The extraction rate of this method is extremely low, only about 1%, and the separation process is complicated, which makes the hyaluronic acid expensive, reaching $5,000/kg, which limits its use in large quantities in cosmetics.


2. Microbial fermentation: use glucose as the carbon source fermentation broth, ferment in the medium for 48 hours, after the fermentation, filter to remove the mycelium and impurities, and then use simple operations such as alcohol precipitation to obtain high-purity products.


The advantage of hyaluronic acid produced by fermentation method is that the molecular weight can be set according to the product design. The key to the fermentation method lies in the selection of strains, such as Streptococcus and Lactococcus.


3. Chemical synthesis: use natural enzyme polymerization; first use polysaccharide polymers to synthesize "hyaluronic acid oxazepine derivatives", then add water-splitting enzymes to create a complex of derivatives and enzymes, and finally Hyaluronic acid was synthesized by removing the enzyme in the reaction solution at 90°C.

The artificial synthesis method can greatly reduce the manufacturing cost of hyaluronic acid, but the structure is less pure.


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