Freeze Dried NAD Powder

 

Freeze dried NAD powder is oxidized coenzyme I (NAD⁺) processed through freeze-drying technology. It has a molecular formula of C₂₁H₂₇N₇O₁₄P₂ and a molecular weight of 663.43 g/mol. Its crystal structure can maintain stability for five years under vacuum conditions of -80°C.

 

Process advantages:

 

• Moisture content <0.5% (measured by Karl Fischer method)
• Biological activity retention rate >98% (HPLC detection)
• Reconstitution time <30 seconds (normal saline medium)

 

Storage conditions:

 

Storage conditions	Validity period	Activity decay rate
4℃, protected from light	36 Months	≤5%
25℃ original packaging	18 Months	≤12%
-20℃ inert gas protection	60 Months	≤2%

 

 

1. Cellular energy hub

(1) Mitochondrial metabolism regulation

• As a key coenzyme of the TCA cycle, each molecule of freeze dried NAD powder can drive the production of 10 molecules of ATP.
• Enhance the activity of the complex and increase the efficiency of the electron transport chain by 23%.

 

(2) Glucolipid metabolism balance

• Activate SIRT1 deacetylase and promote fatty acid oxidation in the PPAR-α pathway.
• Inhibiting mTORC1 signaling improves insulin resistance and reduces blood sugar in diabetes models by 41%.

 

2. DNA repair and anti-aging

(1) PARP1 activation mechanism

• The repair efficiency of single-strand breaks is increased by 3.2 times.
• The telomere wear rate is reduced to 0.3kb/year.

 

(2) Epigenetic regulation

• Maintain histone H3K9 acetylation levels and delay the appearance of cellular senescence markers (SA-β-gal).
• Freeze dried NAD powder can increase the reprogramming efficiency of induced pluripotent stem cells from 2% to 15%.

 

3. Neuroprotective function

 

• Inhibit α-synuclein aggregation.
• Promote BDNF secretion and increase hippocampal neuron synapse density by 37%.

 

 

Form	Molecular properties	Bioavailability	Application
Freeze Dried NAD Powder	Oxidation state, direct donor	12-15%	Critical Care/Cell Engineering
NMN	Single nucleotide precursor	38-42%	Anti-aging health products
NR	Ribose modified type	25-30%	Metabolic syndrome
NADH	Reduced state, poor membrane penetration	＜5%	Chronic disease
NAD+liposomes	Nano-coated sustained release	61-65%	Neurodegenerative diseases

 

 

1. Cross-blood-brain barrier vector

• Glucose-modified nanoparticles increase brain concentration by 8.7 times.
• Focused ultrasound technology to open the blood-brain barrier increases AUC0-24h by 320%.

 

2. Intestinal targeted release technology

• Gastric acid-resistant enteric-coated microspheres (colon release rate >95%)
• Probiotic synthesis system.

3. Transdermal delivery system

• Iontophoresis patch, 24-hour steady-state blood drug concentration.
• Microneedle array, the accumulation amount in the dermis reaches 82% of intravenous injection.

 

 

Shaanxi Fruiterco Biotechnology Co., Ltd. is an export-oriented enterprise mainly producing plant extracts, health supplement raw materials, and cosmetic raw materials. The company has its own factory and also collaborates with other factories, supporting customer factory visits.

 

We can provide our customers with more than 500 products annually, which are exported to more than 40 countries and regions in North America, Europe, Oceania, South America and Asia. For any product inquiries, please send an email to Email: info@fruiterco.com.

 

 

 

 

Our products have obtained Organic, Halal, Kosher, HACCP, and USDA certifications. The company has also successfully passed ISO 22000 certification for food safety management systems. We are committed to providing our customers with high-quality products and support independent re-testing to ensure product quality.

 

 

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