Palmitoyl Hexapeptide-12 Powder

 

Palmitoyl hexapeptide-12 powder is a synthetically produced peptide-often referred to as a lipopeptide or palmitoyl oligopeptide-formed by the covalent bonding of palmitic acid to a sequence of six amino acids (Val-Gly-Val-Ala-Pro-Gly). It exhibits excellent transdermal absorption capabilities.

 

Because this hexapeptide sequence repeats as many as six times within the molecular structure of human elastin, it is colloquially known in the scientific community as the "spring fragment." This structural characteristic ensures high compatibility with the skin's natural composition, allowing it to be easily recognized and utilized by the skin.

 

 

Item	Specification	Result	Test Methods
Appearance	White Fine Powder	Conforms	Organoleptic
Odor & taste	Characteristic	Conforms	Organoleptic
Mesh size	Through 80 mesh	Conforms	80 mesh screen
Assay	≥98.0%	99.23%	HPLC
Loss on Drying	≤5.00%	3.85%	Drying Method
Microbiological Tests
Total Plate Count	≤5000cfu/g	Conforms	Bacterial culture
Total Yeast & Mold	≤100cfu/g	Conforms	Bacterial culture
E.Coli	Negative	Conforms	Bacterial culture
Salmonella	Negative	Conforms	Bacterial culture
Staphylococcus	Negative	Conforms	Bacterial culture

 

 

1. Anti-wrinkle

It activates the fibroblast TGF-β pathway and stimulates the synthesis of Type I and Type III collagen as well as elastin, thereby reducing fine lines, improving facial sagging, and enhancing skin firmness.

 

2. Skin Hydration

Palmitoyl hexapeptide-12 powder upregulates the expression of hyaluronan synthase, increasing endogenous hyaluronic acid levels and counteracting skin thinning caused by photodamage; this boosts skin moisture content, increases epidermal thickness, and strengthens the skin barrier.

 

3. Promotes Wound Healing

It exerts a chemotactic effect, inducing the migration of fibroblasts and monocytes to specific sites for tissue renewal, thereby accelerating wound healing and improving the condition of scars and inflamed areas.

 

4. Soothes Dynamic Wrinkles

It competitively binds to the SNAP-25 protein, inhibiting muscle-contraction wrinkles caused by the excessive release of neurotransmitters; this reduces the force of muscle contractions and softens expression lines.

 

 

1. High-end anti-aging serums:

Often formulated with ingredients like Pro-Xylane and Vitamin E, it specifically targets deep wrinkles such as nasolabial folds and forehead lines.

 

2. Eye and targeted care:

It can be incorporated into eye creams or hand creams to address eyelid sagging, dynamic crow's feet, and signs of aging on the hands.

 

3. Post-procedure recovery:

It is used in skincare following aesthetic treatments-such as microneedling or laser therapy-to accelerate the restoration of the skin barrier and tissue repair.

 

4. Daytime hydration and early anti-aging:

Palmitoyl hexapeptide-12 powder can be combined with acetylated hyaluronic acid or ceramides to enhance daytime moisture retention and early anti-aging benefits.

 

5. Recommended Concentration:

The recommended usage level in creams or gels is typically 0.1%–0.5% (or 100 ppm–500 ppm).

 

6. Incompatibilities:

Direct mixing with ingredients that are strongly acidic (pH < 3) or strongly alkaline (pH > 9) should be avoided. Compatibility with high concentrations of metal ions (such as zinc sulfate) is also not recommended, as this may cause the peptides to precipitate or lose their activity.

 

 

Fruiterco is an export company that mainly produces plant extracts, health product raw materials, and cosmetic raw materials. The company has a 20+ professional service after-sales team.

 

Our products are sold to North America, Europe, Australia, South America and Asia. Our products have passed quality inspection and also support customer re-inspection. Email: info@fruiterco.com.

 

 

 

Our products have obtained Organic, Halal, Kosher, HACCP, and USDA certifications. The company has also successfully passed ISO 22000 certification for food safety management systems. We are committed to providing our customers with high-quality products and support independent re-testing to ensure product quality.

 

 

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