Pyrroloquinoline Quinone Powder

 

Pyrroloquinoline quinone powder is produced by Gram-negative bacteria. It has a wide range of nutritional effects on microorganisms, animals and plants, and has antioxidant nutrients.

 

It is a new prosthetic group with physiological functions similar to vitamins. It is widely found in prokaryotes, plants and mammals, such as fermented soybeans or natto, green peppers, kiwis, parsley, tea, papaya, spinach, celery, Breast milk, etc.

 

The biological functions of PQQ are mainly concentrated in two aspects. First, it can support the growth and development of mitochondria and stimulate the rapid growth of human cells; second, it has good antioxidant properties, which can help remove free radicals and reduce cell damage.

 

These two functions make it play a powerful role in brain health, cardiovascular health, metabolic health and other aspects. Because the body cannot synthesize PQQ itself, it can be supplemented through dietary supplements. These supplements are usually in powder form and are prepared through microbial fermentation.

 

 

Analysis	Specification	Result	Test method
Active ingredients
Assay(on dry base)	99.0% Min	99.8%	HPLC
Physical control
Appearance	Reddish Brown Powder	Reddish Brown Powder	Visual
Identification	Positive	Positive	IR
Water	12% Max	10.20%	GC
Chemical Control
Heavy metals	10 ppm Max	<10 ppm	AAS
As	1.5 ppm Max	<1.5 ppm	AAS
Hg	0.2 ppm Max	<0.2 ppm	AAS
Cd	0.3 ppm Max	<0.30 ppm	AAS
Pb	1.0 ppm Max	<1.0 ppm	AAS
Microbiological Control
Total Plate Count	1,000cfu/g Max	<1,000cfu/g	AOAC
Yeast&Mold	100cfu/g Max	<100cfu/g	AOAC
Coliform	100cfu/g Max	<100cfu/g	AOAC
E.coli	Negative/10g	Negative	AOAC
Salmonella sp	Negative/25g	Negative	AOAC
Staph Aureus	Negative/10g	Negative	AOAC
Conclusion	Complies with the standards.
Packing and Storage
Packing: Pack in paper-carton and two plastic-bags inside.
Shelf life: 2 year when properly stored.
Storage: Store in a well-closed place with constant low temperature and no direct sun light.

 

 

1. Antioxidant properties
PQQ has a strong ability to scavenge peroxides, which can protect mitochondria from oxidative damage; inhibits lipid peroxides; Protects cardiomyocytes from damage caused by ischemia-reperfusion

 

It protects the redox site of oxidized NMDA receptors, thereby promoting the recovery of spinal cord injury and preventing cerebral ischemia and hypoxia.

 

At the same time, PQQ can also protect the heart against myocardial ischemia and myocardial infarction, all thanks to the antioxidant capacity of PQQ.

 

2. Liver protection
Pyrroloquinoline quinone powder protects the liver against alcohol- and carbon tetrachloride-induced liver damage and TAA-induced liver fibrosis.

 

3. Neuroprotective effect
PQQ can improve the neuronal damage caused by the oxygen glucose deprivation model, reduce the change of Nissl body content caused by D-galactose treatment, inhibit neuronal degeneration, weaken the neuronal damage caused by β amyloid, and help promote the secretion of neurotrophic factors.

 

In addition, PQQ can also significantly improve the memory function of rats, and has obvious memory retention and dementia prevention effects.

 

 

4. Anti-inflammatory
PQQ can scavenge ROS and resist inflammatory damage caused by oxidative stress. When pyrroloquinoline quinone powder is lacking in the diet, the content of interleukin 2 in the body is significantly reduced. When PQQ is added, spleen cells respond better to mitogen A and lipopolysaccharide.

 

Adding PQQ to parenteral nutrition can increase the number of lymphocytes in Peyer's patches. The number of cells, as well as CD4+ and CD8+ cells in Peyer's patches, and can restore the integrity of lymphoid organs related to the intestine to a certain extent.

 

5. Promote nerve growth
Nerve growth factor (NGF) is the earliest discovered and most thoroughly researched neurotrophic factor. It has the dual biological functions of neuronal nutrition and neuroprotection.

 

Pyrroloquinoline quinone powder plays an important role in the growth, development, differentiation, regeneration and biological functions of central and peripheral neurons.

 

Functionally specific expression plays an important regulatory role. Experiments have shown that PQQ can stimulate L-M cells and Schwann cells to produce NGF in vitro.

 

 

Shipping pictures, shipping country, shipping packaging

 

 

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