What Are The Functions Of NAC Besides Resolving Phlegm?
Jan 10, 2025
What is N acetyl cysteine powder?
N acetyl l cysteine powder is an active ingredient in phlegm-reducing medicine. It is also an N-acetylated derivative of cysteine, which can be referred to as NAC, and is the precursor of glutathione (GSH).
It can split mucin molecules through sulfhydryl exchange between sulfhydryl groups and mucin. It also has a certain decomposition effect on DNA fibers, thereby reducing the viscosity of sputum. It has a strong dissolving effect on mucus and viscous secretions.
Benefits:
1. Supplement glutathione
Studies have found that glutathione is the most powerful and common antioxidant in the human body. It can help the human body fight cancer, anti-tumor, anti-aging, enhance immunity, etc. However, as we age, the content of glutathione in the body will gradually decrease, and we need to supplement it with other products.
However, the effect of directly supplementing glutathione is not good. It will be hydrolyzed by gamma-glutamyl transferase in the intestine and liver, and its bioavailability is low.
Supplementing nac bulk powder can supplement glutathione from the side, because NAC can synthesize glutathione in the liver, thereby eliminating excess reactive oxygen species (ROS), and ultimately achieves hepatoprotective effects.
2. Promote recovery after drinking
NAC can promote recovery after drinking while preventing or alleviating the discomfort of a hangover because NAC can reduce oxidative stress, thereby preventing some of the damaging effects of alcohol, but it cannot completely prevent alcohol-induced liver damage.
3. Protect respiratory tract
NAC can reduce the apoptosis of type I alveolar epithelial cells induced by nicotine, and can also inhibit the apoptosis of type II alveolar epithelial cells induced by cigarette extract. NAC powder bulk can maintain sufficient glutathione in the lungs and respiratory tract, protecting the respiratory tract through antioxidant and anti-inflammatory effects.
4. Stabilize emotions
Glutamic acid imbalance is a contributing factor to mood and cognitive problems. NAC has an impact on the levels of the neurotransmitter glutamate in the brain. Modulating glutamate levels can better alleviate anxiety, depression and other mental health conditions.

5. Whitening
Direct supplementation of glutathione cannot be absorbed. Supplementation of NAC indirectly increases the body's glutathione level. Glutathione can inhibit tyrosinase and eliminate free radicals, thereby reducing the formation of melanin and achieving whitening effects.
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References:
1. GIROUARD H, CHULAK C, WU L, et al. N-acetylcysteine improves nitric oxide and alpha-adrenergic pathways in mesenteric beds of spontaneously hypertensive rats[J]. Am J Hypertens, 2003, 16(7):577-584.
2. Mansouri MD, Darouiche Re.In vitro antimicrobial activity of N-acetylcysteine against bacteria colonising central venous catheters[J].Int J Antimicrob Agents, 2007, 29(4): 474-476.
3. Griffith OW, Novogrodsky A, Meister A. Translocation of glutathione from lymphoid cells that have markedly different gamma-glutamyl transpeptidase activities. Proc Natl Acad Sci U S A. 1979 May;76(5):2249–2252.
4. Demiralay R , Nesrin Gürsan, Erdem H . The effects of erdosteine, N-acetylcysteine, and vitamin E on nicotine-induced apoptosis of pulmonary cells[J]. 2006, 219(1-3):197-207.
5. Rostami R , et al. Enhanced oxidative stress in Hashimoto's thyroiditis: inter-relationships to biomarkers of thyroid function.[J]. Clinical Biochemistry, 2013, 46(4-5):308-312.
6. Arjinpathana N , Asawanonda P . Glutathione as an oral whitening agent: A randomized, double-blind, placebo-controlled study[J]. Journal of Dermatological Treatment, 2012, 23(2):97-102.






