Agaricus Blazei Mushroom Extract

 

Agaricus blazei mushroom extract is a saprophytic fungus that grows in summer and autumn. It lives in a high-temperature, humid, and ventilated environment. It has an almond aroma and a crisp and tender taste.

 

The protein composition includes 18 kinds of amino acids, 8 kinds of essential amino acids for the human body are complete, and it also contains a variety of vitamins and ergosterol.

 

It is mainly an active substance prepared through the following process:

1. Water extraction process: 60-100℃ hot water extraction
2. Alcohol extraction process: Extraction using 30-95% ethanol solution
3. Compound extraction: combined/ultrasonic microwave assisted technology

 

 

1. Polysaccharides
Contains bioactive polysaccharides including β-glucans and acidic heteropolysaccharides. These compounds stimulate cytokine production (e.g., interferon-γ) through TLR4 receptor activation, enhancing cellular immunity by 40-65% based on in vitro PBMC assays.

2. Sterols
Six identified ergosterol derivatives (e.g., blazeispirols A-C) demonstrate:

• 58-72% growth inhibition against HepG2/MCF-7 cancer cells (IC₅₀=12.8-28.4 μM)
• Osteoclastogenesis suppression via RANKL/OPG pathway modulation (50 mg/kg/day in ovariectomized rat models)

3. Nucleic Acids
Adenosine-enriched fractions (0.35%):

• Binds carcinogens (e.g., 89% aflatoxin B1 adsorption)
• Reduces systolic BP by 11.2 mmHg and LDL-C by 19.4% in hyperlipidemic patients (12-week RCT)

 

 

ITEM	SPECIFICATION	TESTING METHOD
Assay(Polysaccharides)	30% Min	CP2010-UV
Physical & Chemical Control
Appearance	Yellow-brown Fine Powder	Visual
Odor	Characteristic	Organoleptic
Tasted	Characteristic	Organoleptic
Sieve Analysis	100% pass 80 mesh	80mesh screen
Loss on Drying	7% Max.	GB 5009.3
Ash	9% Max.	GB 5009.4
As	1.0ppm Max	GB 5009.11
Pb	2.0ppm Max	GB 5009.12
Hg	1.0ppm Max.	GB 5009.17
Cd	0.1ppm Max	GB 5009.15
Microbiological
Total Plate Count	10000cfu/g Max.	GB 4789.2
Yeast & Mould	100cfu/g Max	GB 4789.15
E.Coli	Negative	GB 4789.3
Staphylococcus	Negative	GB 29921
Salmonella	Negative in 10 g	AOAC/Neogen Elisa
Yeast & Mold	1000cfu/g Max	AOAC/Petrifilm
E.Coli	Negative in 1g	AOAC/Petrifilm
Staphlococcus Aureus	Negative	CP2015

 

 

1. Improve hematopoietic function
It is a very good choice for female friends to consume some Agaricus blazei in their daily routine. Female friends can achieve a good purpose of promoting hematopoietic function by using Agaricus blazei.

 

2. Protect the liver
As social pressure increases, many people use alcohol to relieve stress. Long-term drinking can cause liver damage, and in severe cases, alcoholic liver problems may occur. Studies have found that daily consumption of agaricus blazei mushroom extract can achieve a good protective effect on the liver and kidneys.

 

 

3. Enhance human immunity
Agaricus blazei can achieve a very good immune-enhancing effect, which can greatly reduce the probability of self-esteem and various diseases. In particular, it can effectively enhance its own ability to fight influenza viruses in winter and reduce its own probability of colds and fevers.

 

This is because Agaricus blazei contains very rich active polysaccharide substances, which can achieve a good solidifying effect and enhance human immunity.

 

4. Prevent and fight cancer
As modern living habits become more and more unhealthy, the incidence of cancer is gradually increasing. It is recommended that everyone eat some agaricus blazei in daily life, which can achieve a good anti-cancer effect.

 

This is because agaricus blazei mushroom extract is very rich in selenium and anti-cancer factors, and can also achieve good effects on people by inhibiting the spread of cancer cells.

 

 

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