Maitake Mushroom Extract

 

Maitake mushroom extract is a product extracted through biotechnology from the medicinal fungus Grifola frondosa. It is mainly used in the fields of nutritional supplements, functional foods and pharmaceutical research and development.

 

 

1. Polysaccharides (30-50%)

• β-Glucan: content must be ≥30%
• Heteropolysaccharide complex: contains protein-bound polysaccharides with a molecular weight of approximately 1000 kDa

2. Triterpenoids (2-5%)

• Representative ingredients: Grifolin, Neogrifolin
• Structural characteristics: Lanostane type tetracyclic triterpene with high oxidation modification

3. Functional protein (accounting for 8-15%)

• Immunomodulatory proteins: such as Maitake Protein-bound Polysaccharide (MPBP)
• Molecular weight range: 10-150 kDa

4. Trace active substances

• Antioxidant ingredient: ergothioneine, content 0.1-0.3%
• Vitamins: Vitamin D₂, the content after conversion by UV irradiation can reach 2000 IU/g
• Mineral elements: organic germanium, Ge-132, content 50-200 ppm

 

 

Analysis	Specification	Result	Test method
Physical Description
Appearance	Yellow brown powder	Yellow brown powder	Visual
Odor & Taste	Characteristic	Characteristic	Organoleptic
Particle size	100% pass 80 mesh	100% pass 80 mesh	80 mesh
Chemical Tests
Beta glucan	30.0% Min	31.13%	Megazyme
Loss on drying	7.0% Max	3.24%	GB5009.3
Ash	9.0% Max	5.68%	GB5009.4
Heavy metals
As	1.0mg/kg Max	<1.0mg/kg	ISO17294 ICP/MS
Pb	2.0mg/kg Max	<2.0mg/kg	ISO17294 ICP/MS
Hg	0.1mg/kg Max	<0.1mg/kg	EN13806 AAS
Cd	1.0mg/kg Max	<1.0mg/kg	ISO17294 ICP/MS
Microbiology Control
Total plate count	10,000cfu/g Max	<10,000cfu/g	GB 4789.2
Yeast & Mold	100cfu/g Max	<100cfu/g	GB 4789.15
Coliforms	Negative	Negative	GB 4789.3
Pathogenic bacteria	Negative	Negative	GB4789.4, GB4789.10
Conclusion	Complies with the standards.
General Status	Non-GMO, ISO Certificated.
Packing and Storage
Packing: Pack in paper-carton and two plastic-bags inside.
Shelf life: 2 year when properly stored.
Storage: Store in a well-closed place with constant low temperature and no direct sun light.

 

1. Immunoregulatory Activity
The β-glucan component demonstrates immunomodulatory effects through binding to macrophage surface Dectin-1 receptors, subsequently activating the NF-κB signaling pathway.

2. Hepatic and Cardiovascular Protection
Characterized by elevated selenium and chromium concentrations, the extract exhibits protective effects on hepatic and pancreatic tissues. Clinical observations indicate preventive potential against cirrhosis, diabetes mellitus, Kashin-Beck disease, and specific cardiovascular pathologies.

3. Antineoplastic Mechanisms

Maitake mushroom extract demonstrates dual anti-cancer mechanisms:

• Immunostimulatory: Activates phagocytes, NK cells, and cytotoxic T lymphocytes, inducing secretion of leukocyte mediators, IFN-γ, and TNF-α
• Pro-apoptotic: Directly triggers neoplastic cell apoptosis through intrinsic pathways

4. Antiviral Efficacy Against Influenza
Contained α-glucan constituents enhance host immune response to influenza viruses through:

• Improved immunological memory formation
• Synergistic enhancement of conventional antiviral therapies

5. Metabolic Regulation
Maitake mushroom extract polysaccharide fraction containing β-(1-3)-D-glucan and β-(1-6)-D-glucan-protein complexes demonstrates:

• Significant hypoglycemic activity
• Complementary effects from unsaturated fatty acids:
• Cholesterol-lowering properties
• Antiatherosclerotic action
• Enhanced insulin sensitivity

 

 

There are many benefits of taking Grifola Grifola, but it needs to be taken according to the dosage. If it is overdosed for a long time, it will cause physical discomfort symptoms, such as nausea and vomiting, diarrhea, abdominal distension and pain, etc.

 

 

 

Fruiterco is an export company that mainly produces plant extracts, health product raw materials, and cosmetic raw materials. The company has a 20+ professional service after-sales team.

 

Our products are sold to North America, Europe, Australia, South America and Asia. Our products have passed quality inspection and also support customer re-inspection. Email: info@fruiterco.com.

 

 

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