Threonine Powder

 

Threonine, abbreviated as Thr, is sold in our company as threonine powder, which is an essential amino acid among the 20 standard α-amino acids. Its molecular structure features are:

 

• Polar side chain: a unique structure containing β-hydroxyl (-OH)
• Stereoisomerism: the natural form is L-threonine
• Metabolic dependence: humans and mammals cannot synthesize it independently and need to be ingested through diet

 

Biological distribution characteristics:

 

• Tissue concentration: the normal range in plasma is 85-210μmol/L.
• Food sources: turkey (1.2g per 100g), chia seeds (0.7g), whey protein (4.3g/100g).

 

 

Analysis	Specification	Result	Test Methods
Physical Description
Appearance	White crystalline powder, slightly sweet taste	White crystalline powder, slightly sweet taste	USP
Specific rotation [α]D20	-26.7°~-29.1°	-27.7°	USP
PH value	5.0~6.5	5.7	USP
Chemical Tests
Assay	98.5~ 101.5 %	99.78%	USP
Loss on drying	0.20% Max	0.13%	USP
Residue on ignition	0.40% Max	0.04%	USP
Chloride(Cl)	0.05% Max	<0.05%	USP
Sulfate(SO4)	0.03% Max	<0.03%	USP
Heavy metals (Pb)	15.0ppm Max	<15ppm	USP
Conclusion	Complies with the USP Standard.
General Status	Non-GMO, Non-irradiation, ISO.
Packing and Storage
Packing: Pack in paper-carton and two plastic-bags inside.
Shelf life: 2 year when properly stored.
Storage: Store in a well-closed place with constant low temperature and no direct sun light.

 

 

1. Regulation of protein structure and function

• Structural support: As a hydroxylation modification site for collagen and elastin, threonine powder maintains more than 50% of the mechanical strength of the dermis.
• Enzyme activity regulation: Participates in phosphorylation signaling pathways (such as MAPK pathways) and regulates the activity expression of 300+ enzymes.

 

2. Enhance immunity

• Antibody synthesis: As the second limiting amino acid of immunoglobulin G, it increases the antibody production rate by 37%.
• Mucosal defense: Promotes the synthesis of intestinal mucin MUC2 and reduces the risk of pathogenic bacteria colonization.

 

3. Metabolic system optimization

• Lipid metabolism: Accelerates the secretion of very low-density lipoprotein in the liver by activating PPARα receptors.
• Detoxification mechanism: As a methyl donor for glycine binding reaction, threonine powder increases the activity of phase II detoxification enzyme UGT.

 

4. Nervous and motor function

• Neurotransmitter precursor: Participates in the synthesis of 5-hydroxytryptamine and improves depression.
• Exercise recovery: Reduces the increase in creatine kinase (CK) levels after exercise by 42%, shortening the DOMS recovery cycle.

 

 

1. Collagen hydroxylation
Threonine is a key donor for the synthesis of hydroxyproline in collagen. It consumes 0.12g of threonine for every 1g of collagen fiber produced by prolyl hydroxylase catalysis.

 

2. Elastin cross-linking
During the cross-linking process of elastin, threonine powder forms desmosin through an aldehyde condensation reaction mediated by LOX enzyme, which enhances the skin's resilience.

 

3. Stratum corneum barrier construction
As an important component of profilin, a precursor of filaggrin, threonine reduces the transepidermal water loss rate to 8.3g/(m²·h) by regulating the synthesis of natural moisturizing factor in the stratum corneum.

 

4. Accelerate wound healing
In the skin defect model, threonine activates the mTORC1 signaling pathway, increases the migration speed of fibroblasts, promotes the secretion of vascular endothelial growth factor, and shortens the wound healing time.

 

5. Repair light damage
After ultraviolet irradiation, threonine powder enhances the activity of glutathione peroxidase through the Nrf2/ARE pathway, improves the efficiency of neutralizing ROS, has a good anti-inflammatory effect, and reduces the damage caused by sunburn.

 

6. Activation of aquaporins
Threonine regulates AQP3 expression through phosphorylation, increasing the water gradient diffusion efficiency from the epidermal basal layer to the stratum corneum by 33%, especially improving the phenomenon of dry and flaky skin in winter.

 

 

Fruiterco can provide efficient and convenient delivery methods for the products that customers need. For example: air, sea, express, you can rest assured of product quality problems during transportation.

 

We have professional business staff to communicate with you about your product needs and understanding. There is a professional mailbox system, you can leave a message at any time, we will reply as soon as we see it. Email: info@fruiterco.com.

 

 

 

Our products are certified organic, halal, kosher, USDA. Our company has passed ISO22000 quality management system certification. We are able to provide our customers with high-quality products and support them in retesting ingredients to ensure product quality.

 

 

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