Acetyl Hexapeptide-38

 

Acetyl Hexapeptide-38 is a bioactive peptide capable of targeted stimulation of local fat synthesis. By upregulating PGC-1α expression, it safely and effectively increases fat volume in specific areas such as the bust, cheeks, and buttocks, making it an ideal cosmetic ingredient for reshaping body contours and restoring a youthful facial appearance.

 

Its amino acid sequence is Ac-Ser-Val-Val-Val-Arg-Thr-NH2, and it was precisely selected from millions of hexapeptides with diverse sequences using a reporter gene assay.

 

In terms of appearance, it typically presents as a white powder with a purity exceeding 98% and excellent water solubility. To preserve its biological activity, it is recommended to store the raw material under refrigeration at 2°C–8°C, or to keep it freeze-dried and protected from light at -20°C.

 

As a cosmetic ingredient that is non-toxic and free from side effects, it does not rely on hormones or phytoestrogens; instead, it achieves a localized volumizing effect through pure cell signaling.

 

 

Items	Standards	Results
Appearance	White to off-white powder	Complies
Identity by ESI-MS	Theoretical MW: 700.84	Complies
Purity (HPLC)	≥95.0%	99.73%
Peptide Content(By N)	≥80.0%	83.17%
Water (K.F.)	≤7.0%	3.74%
Acetic acid content	≤15.0%	8.08%
Lead (mg/kg)	≤10	< 10
Arsenic (mg/kg)	≤2	< 2
Mercury (mg/kg)	≤1	< 1
Cadmium (mg/kg)	≤5	< 5
Total plate count (cfu/g)	≤1000	Complies
Yeast & mould (cfu/g)	≤100	Complies
Conclusion	Conforms to standard	Complies

 

 

The youthful appearance and plumpness of the skin rely heavily on the structural support provided by subcutaneous adipose tissue. With aging, the loss of localized fat leads to facial hollows, deepened wrinkles, and a loss of body contour definition.

 

Research indicates that peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1α) plays a pivotal role in cellular energy metabolism and lipid storage within white adipose tissue.

 

Acetyl hexapeptide-38 significantly stimulates PGC-1α expression; experimental data show it increases PGC-1α levels by approximately 61.1%. Activation of this signaling pathway effectively promotes the differentiation of subcutaneous pre-adipocytes into mature adipocytes, thereby enhancing lipid accumulation capacity.

 

Culturing experiments with pre-adipocytes further confirm that treatment with this ingredient for 10 days results in a significant 32.4% increase in lipid accumulation. By increasing both the number and volume of adipocytes in specific areas, this mechanism physically supports the skin, achieving a naturally voluminous effect.

 

 

1. Facial Contouring and Anti-Aging

In facial formulations, it effectively increases the volume of subcutaneous supporting tissue, corrects cheek hollows caused by fat loss, and smooths out expression lines and wrinkles, resulting in a lifted, supple, and youthful appearance.

 

2. Body Contouring

As a key ingredient in breast and buttock enhancement products, Acetyl Hexapeptide-38 increases adipose tissue volume in specific areas-such as the breasts or buttocks-helping to sculpt attractive body curves.

 

3. Lip Care

It is also suitable for lip care products, creating a natural plumping effect; additionally, as fat in the hands diminishes with age, it serves as an ideal additive for anti-aging hand creams.

 

 

Fruiterco is an export company that mainly produces plant extracts, health product raw materials, and cosmetic raw materials. The company has a 20+ professional service after-sales team.

 

Our products are sold to North America, Europe, Australia, South America and Asia. Our products have passed quality inspection and also support customer re-inspection.

 

 

 

Our company participated in the CPHI exhibition held in Barcelona, ​​Spain, from October 24 to 26, 2023 (Booth No.: 81C25). CPHI is an international exhibition focused on pharmaceutical ingredients, intermediates, finished formulations, and related sectors. It serves as a platform for the pharmaceutical and healthcare industries to showcase the latest products and technologies, expand business partnerships, and exchange industry insights.

 

To enhance our brand influence and demonstrate our capabilities to global clients, we made thorough preparations regarding our products, company profile, and services; consequently, a large number of customers visited our booth to inquire about our products.

 

 

 

Our products have obtained Organic, Halal, Kosher, HACCP, and USDA certifications. The company has also successfully passed ISO 22000 certification for food safety management systems. We are committed to providing our customers with high-quality products and support independent re-testing to ensure product quality.

 

 

 

We are a professional Oligopeptide-68 Powder Supplier; please feel free to contact us via email if you have any requirements for this product. Please contact us: Email: info@fruiterco.com.

 

 

Hot Tags: acetyl hexapeptide-38, China acetyl hexapeptide-38 manufacturers, suppliers, factory, alpha lipoic acid powder, dipotassium glycyrrhizinate powder, magnesium ascorbyl phosphate powder, polyglutamic acid powder, raspberry ketone glucoside, tranexamic acid powder