Acetyl Hexapeptide-39
Product Name: Acetyl Hexapeptide-39
Specification: ≥98%
Appearance: White to off-white powder
CAS: 1382088-38-1
MF: C32H53N9O7
MW: 671.83g/mol
Storage: Store sealed in a dry place, protected from light, at temperatures between -20°C and 8°C.
Grade: Cosmetic Grade
Certificate: ISO, Halal, Kosher
Shelf life: 2 Years
Packing: 1kg/Bag, 25kg/Drum
- Fast Delievery
- Quality Assurance
- 24/7 Customer Service
Product Introduction
What is Acetyl Hexapeptide-39?
In today's pursuit of a perfect physique, many consumers struggle with localized fat accumulation and cellulite, while traditional physical or chemical slimming methods often carry the risk of weight rebound or skin laxity.
Acetyl hexapeptide-39 has emerged as a breakthrough innovation in cosmetic R&D and brand marketing. It is a novel bioactive peptide-appearing as a white powder with a purity exceeding 98%-that demonstrates excellent transdermal absorption potential.
Widely recognized in the cosmetic ingredient industry as an ideal component for anti-cellulite and slimming treatments, it integrates seamlessly into various body care formulations. To preserve its bioactivity, the raw material typically requires storage at low temperatures (2°C–8°C) and protection from light.
COA:
| Items | Standards | Results |
| Appearance | White to off-white powder | Complies |
| Identity by ESI-MS | Theoretical MW: Complies | Complies |
| Purity(HPLC) | ≥98.0% | 99.44% |
| Water(K.E) | ≤7.0% | 6.04% |
| Conclusion | Conforms to standard | Complies |
| Store at | Keep in dark and cool dry place(-20 to 8°C). | |
Acetyl Hexapeptide-39 benefits:
1. Targeted inhibition of PGC-1α expression
Studies demonstrate that this peptide effectively inhibits the expression of peroxisome proliferator-activated receptor gamma coactivator-1α (PGC-1α).
2. Blocking pre-adipocyte differentiation
The reduction in PGC-1α directly lowers the likelihood of pre-adipocytes differentiating into mature adipocytes, thereby curbing the formation of new fat at the source.
Experiments using pre-adipocyte cultures showed that treatment with 0.1 mg/mL of Acetyl Hexapeptide-39 reduced PGC-1α expression by 36% after 10 days and slowed the rate of fat accumulation by 37.5% compared to the control group.
3. Improving skin surface smoothness
Human clinical trials confirm that it significantly reduces the length of the dermal-subcutaneous junction and decreases the fat nodules associated with cellulite, resulting in a smoother, firmer skin surface. In a 3-week study involving 20 female subjects, the use of a cream containing 10 ppm of this ingredient resulted in an 11% reduction in cellulite.
Acetyl Hexapeptide-39 uses:
1. Targeted Contouring Creams/Serums
Designed for areas prone to fat accumulation-such as the thighs, buttocks, and abdomen-these high-concentration, targeted firming serums meet consumer demand for "precision slimming."
2. Anti-Cellulite Body Lotions
Acetyl Hexapeptide-39 combines moisturizing and reparative ingredients to smooth out skin surface irregularities, enhancing both the feel and visual appearance of the skin to restore its smoothness.
3. Facial Contouring and Firming Products
While primarily intended for the body, their gentle formulation also lends itself to the development of targeted facial treatments-such as jawline contouring-to help achieve a sculpted, slim-face effect.
What is the difference in slimming effects between Acetyl Hexapeptide-39 and plant extracts?
| Contrast | Acetyl Hexapeptide-39 | White kidney bean extract | Garcinia cambogia extract |
| Active ingredient |
Cosmetic active peptides |
α-Amylase inhibitor | Hydroxycitric acid (HCA) |
| Uses | External use, apply to the skin | Consume before meals / Meal replacement | Health/ Weight Loss Supplements |
|
Benefits |
Inhibit PGC-1α expression and block preadipocyte differentiation. | Inhibit α-amylase activity and block the breakdown of starch into monosaccharides. | Inhibit ATP-citrate lyase and limit fatty acid synthesis. |
| Safety | High | Relatively high; excreted in the feces |
Relatively low |
Our Advantages:
Fruiterco is an export company that mainly produces plant extracts, health product raw materials, and cosmetic raw materials. The company has a 20+ professional service after-sales team.
Our products are sold to North America, Europe, Australia, South America and Asia. Our products have passed quality inspection and also support customer re-inspection.

Exhibiting at CPHI Worldwide:
Our company participated in the CPHI exhibition held in Barcelona, Spain, from October 24 to 26, 2023 (Booth No.: 81C25). CPHI is an international exhibition focused on pharmaceutical ingredients, intermediates, finished formulations, and related sectors. It serves as a platform for the pharmaceutical and healthcare industries to showcase the latest products and technologies, expand business partnerships, and exchange industry insights.
To enhance our brand influence and demonstrate our capabilities to global clients, we made thorough preparations regarding our products, company profile, and services; consequently, a large number of customers visited our booth to inquire about our products.

Our certificate:
Our products have obtained Organic, Halal, Kosher, HACCP, and USDA certifications. The company has also successfully passed ISO 22000 certification for food safety management systems. We are committed to providing our customers with high-quality products and support independent re-testing to ensure product quality.

contact us:
We are a professional Oligopeptide-68 Powder Supplier; please feel free to contact us via email if you have any requirements for this product. Please contact us: Email: info@fruiterco.com.
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