What Are The Benefits And Side Effects Of Ginger Extract?

 

Ginger extract is a concentrate of active ingredients extracted from the rhizome of Zingiber officinale by modern technology. Common forms include:

 

• Water extract: retains polar components such as Gingerols and is suitable for anti-inflammatory preparations.
• Ethanol extract: rich in Shogaols, used in the field of antioxidants.
• Supercritical CO₂ extract: efficient extraction of volatile components (such as ginger essential oil, including α-gingerene and β-sesquiphellandrene), with a purity of more than 95%.

 

International standard: USP stipulates that the content of 6-gingerol in high-quality extracts must be ≥5%, and the content of ginger essential oil must be ≥1.5% (v/w).

 

1. Phenolic compounds (accounting for 50%-70%)

• 6-gingerol: inhibits COX-2 and 5-LOX dual pathways, blocks the production of prostaglandins and leukotrienes (anti-inflammatory potency is 1.5 times that of aspirin).
• 6-shogaol: thermal transformation product, enhances thermal metabolism by activating TRPV1 receptors and promotes fat oxidation.

 

2. Volatile terpenes (accounting for 10%-25%)

• α-gingerene: regulates intestinal 5-HT3 receptors and relieves nausea and vomiting caused by chemotherapy.
• β-sesquiterene: inhibits NF-κB nuclear translocation and reduces TNF-α and IL-6 expression.

 

3. Polysaccharides and trace elements

• Ginger extract powder polysaccharides: activate the TLR4 signaling pathway of macrophages and enhance phagocytic function.
• Manganese and zinc: as cofactors of SOD enzyme, they scavenge superoxide free radicals. In vitro experiments show that its antioxidant capacity is 1.8 times that of vitamin E.

 

 

1. Digestive system

• Promote gastrointestinal motility: It can accelerate gastric emptying through cholinergic mechanisms.
• Anti-Helicobacter pylori: It can destroy bacterial urease activity, and the eradication rate is increased to 92% when used in combination with antibiotics.

 

2. Metabolism and chronic disease intervention

• Blood sugar regulation: pure ginger extract can inhibit the dual targets of α-amylase and α-glucosidase.
• Anti-atherosclerosis: It can reduce the expression of LOX-1 receptors in the vascular endothelium and block the deposition of oxidized LDL.

 

3. Neuroprotection and anti-aging

• Inhibit β-amyloid protein: Clear Aβ deposition in the brain by enhancing the activity of Neprilysin enzyme (memory test of Alzheimer's disease model mice improved by 39%).
• Prolong telomere length: Activate telomerase reverse transcriptase (TERT) and delay cell aging.

 

4. Exercise and women's health

• Relieve dysmenorrhea: block excessive release of PGF2α in uterine smooth muscle.
• Recovery after exercise: reduce serum CK and LDH levels, reduce the duration of delayed muscle soreness, and speed up recovery after exercise.

 

 

1. Gingerol activates TRPV1 receptors:

It stimulates gastric acid secretion (increases 30%-50%), causing symptoms such as heartburn and acid reflux, and increases the risk of taking it on an empty stomach.

 

2. Protease inhibition effect:

High concentrations of gingerol powder inhibit trypsin activity (IC50=25 μM), leading to protein indigestion.

 

3. Enhanced fibrinolytic activity:

It can upregulate tissue plasminogen activator (t-PA) and promote thrombus resolution.

 

4. Allergen characteristics:

Ginger protein is recognized by the WHO as a Class II allergen, with a sensitization rate of about 0.3%-0.7%, manifested as urticaria or respiratory edema.

 

5. Exacerbation of biliary diseases
Stimulates the secretion of cholecystokinin (CCK), induces biliary colic, and the risk of acute attacks in patients with gallstones increases by 4.8 times.

 

 

Fruiterco is an export company that mainly produces plant extracts, health product raw materials, and cosmetic raw materials. The company has a 20+ professional service after-sales team.

 

Our products are sold to North America, Europe, Australia, South America and Asia. Our products have passed quality inspection and also support customer re-inspection. If you want to buy ginger extract, you can contact us: Email: info@fruiterco.com.

 

 

1. https://www.webmd.com/vitamins/ai/ingredientmono-961/ginger

2. https://www.mountsinai.org/health-library/herb/ginger

3. https://pmc.ncbi.nlm.nih.gov/articles/PMC3329925/

4. https://www.nccih.nih.gov/health/ginger

5. https://ro.co/erectile-dysfunction/ginger-benefits-sexually/

6. https://www.health.com/condition/skin-cancer/red-hair-pain-melanoma-vitamin-d

7. https://www.medicalnewstoday.com/articles/265990

8. https://www.hopkinsmedicine.org/health/wellness-and-prevention/ginger-benefits