What Are The Effects And Uses Of Chitosan Powder?
Mar 04, 2025
What is Chitosan?
Chitosan powder is the product of chitin after deacetylation. Its chemical name is β-(1→4)-2-amino-2-deoxy-D-glucan. It is water-soluble when the degree of deacetylation (DD) is ≥55%. Its molecular weight ranges from 20-1000 kDa, and its crystallinity is 75%. It is the only alkaline polysaccharide with positive charge in nature.
2. Chitosan source
- Marine organisms: shrimp and crab shells (global annual production is 2 million tons, China accounts for 65%).
- New extraction: fungal cell walls (such as Aspergillus niger) and insect exoskeletons (silkworm pupae, locusts).
2. Functional properties
- Biological adhesion: electrostatic binding time with mucosa is greater than 8 hours.
- pH responsiveness: dissolution rate is greater than 90% in gastric acid environment (pH 1.2), and gel is formed in the intestine (pH 6.8).
- Chelating ability: 600mg heavy metal ions (such as Pb²⁺, Cd²⁺) can be bound per gram.
chitosan powder benefits:
1. Biomedical field
(1) Wound repair system
- Activates macrophage M2 polarization, speeding up wound healing by 40%.
- Promotes type III collagen deposition.
(2) Precision drug delivery
- Targeted carrier: Folic acid-modified pure chitosan powder nanoparticles have a liver cancer targeting efficiency of 89%.
- Controlled release technology: Oral insulin formulations achieve 12-hour stable glucose control.
(3) Metabolic regulation
It can combine with dietary fat to inhibit pancreatic lipase activity
2. Environmental and industrial applications
(1) Wastewater treatment
- The efficiency of removing microplastics is 94%.
- The removal rate of heavy metals in industrial wastewater, such as Cr⁶⁺, is 99.8%.
(2) Food preservation technology
- Antibacterial film inhibits the formation of Escherichia coli biofilm.
- The shelf life of strawberries is extended to 21 days.
(3) Agricultural efficiency enhancement
- Chitosan-selenium nanofertilizer increases the selenium content of rice by 8 times.
- Induce plant disease resistance genes.
Risks and hazards:
1. Allergy risk
- The cross-reaction rate of people allergic to crustaceans is 18.7%.
- Symptoms: urticaria (incidence 3.2%), respiratory edema (0.7%).
2. Nutritional interference
- Binding fat-soluble vitamins, vitamin A absorption rate decreased by 29%.
- Chelating essential minerals such as iron and zinc, serum ferritin decreased by 15%.
3. Digestive tract reactions
- High doses (>5g/day) cause abdominal distension and constipation.
- Chitosan powder bulk should be used with caution in patients with irritable bowel syndrome.
4. Contraindications for special populations
- Pregnant women: may affect placental angiogenesis.
- Immunosuppressed patients: activation of the TLR4 pathway potentially interferes with immunotherapy.
About Us:
Fruiterco is an export company that mainly produces plant extracts, health product raw materials, and cosmetic raw materials. The company has a 20+ professional service after-sales team.
Our products are sold to North America, Europe, Australia, South America and Asia. Our products have passed quality inspection and also support customer re-inspection. If you want to buy chitosan powder, you can contact us: Email: info@fruiterco.com.
References:
1. https://www.webmd.com/vitamins/ai/ingredientmono-625/chitosan
2. https://jhpn.biomedcentral.com/articles/10.1186/s41043-025-00797-3
3. https://www.sciencedirect.com/science/article/abs/pii/S0144861796000331
4. https://www.webmd.com/vitamins-and-supplements/chitosan-uses-and-risks
5. https://www.medicinenet.com/chitosan_benefit_kidneys_are_there_side_effects/article.htm
6. https://www.rxlist.com/supplements/chitosan.htm#:~:text=Kidney%20failure.,are%20receiving%20long%2Dterm%20hemodialysis.
7. https://pmc.ncbi.nlm.nih.gov/articles/PMC6431530/#:~:text
8. https://www.verywellhealth.com/chitosan-everything-you-need-to-know-7866985






