What Are The Effects And Uses Of Chitosan Powder?

Mar 04, 2025

What is Chitosan?

 

Chitosan powder is the product of chitin after deacetylation. Its chemical name is β-(1→4)-2-amino-2-deoxy-D-glucan. It is water-soluble when the degree of deacetylation (DD) is ≥55%. Its molecular weight ranges from 20-1000 kDa, and its crystallinity is 75%. It is the only alkaline polysaccharide with positive charge in nature.

 

2. Chitosan source

  • Marine organisms: shrimp and crab shells (global annual production is 2 million tons, China accounts for 65%).
  • New extraction: fungal cell walls (such as Aspergillus niger) and insect exoskeletons (silkworm pupae, locusts).

 

2. Functional properties

  • Biological adhesion: electrostatic binding time with mucosa is greater than 8 hours.
  • pH responsiveness: dissolution rate is greater than 90% in gastric acid environment (pH 1.2), and gel is formed in the intestine (pH 6.8).
  • Chelating ability: 600mg heavy metal ions (such as Pb²⁺, Cd²⁺) can be bound per gram.

 

chitosan powder benefits:

 

1. Biomedical field

(1) Wound repair system

  • Activates macrophage M2 polarization, speeding up wound healing by 40%.
  • Promotes type III collagen deposition.

 

(2) Precision drug delivery

  • Targeted carrier: Folic acid-modified pure chitosan powder nanoparticles have a liver cancer targeting efficiency of 89%.
  • Controlled release technology: Oral insulin formulations achieve 12-hour stable glucose control.

 

(3) Metabolic regulation

It can combine with dietary fat to inhibit pancreatic lipase activity

 

2. Environmental and industrial applications

 

(1) Wastewater treatment

  • The efficiency of removing microplastics is 94%.
  • The removal rate of heavy metals in industrial wastewater, such as Cr⁶⁺, is 99.8%.

 

(2) Food preservation technology

  • Antibacterial film inhibits the formation of Escherichia coli biofilm.
  • The shelf life of strawberries is extended to 21 days.

 

(3) Agricultural efficiency enhancement

  • Chitosan-selenium nanofertilizer increases the selenium content of rice by 8 times.
  • Induce plant disease resistance genes.

 

Risks and hazards:

 

1. Allergy risk

  • The cross-reaction rate of people allergic to crustaceans is 18.7%.
  • Symptoms: urticaria (incidence 3.2%), respiratory edema (0.7%).

 

2. Nutritional interference

  • Binding fat-soluble vitamins, vitamin A absorption rate decreased by 29%.
  • Chelating essential minerals such as iron and zinc, serum ferritin decreased by 15%.

 

3. Digestive tract reactions

  • High doses (>5g/day) cause abdominal distension and constipation.
  • Chitosan powder bulk should be used with caution in patients with irritable bowel syndrome.

 

4. Contraindications for special populations

  • Pregnant women: may affect placental angiogenesis.
  • Immunosuppressed patients: activation of the TLR4 pathway potentially interferes with immunotherapy.

 

About Us:

 

Fruiterco is an export company that mainly produces plant extracts, health product raw materials, and cosmetic raw materials. The company has a 20+ professional service after-sales team.

 

Our products are sold to North America, Europe, Australia, South America and Asia. Our products have passed quality inspection and also support customer re-inspection. If you want to buy chitosan powder, you can contact us: Email: info@fruiterco.com.

 

References:

 

1. https://www.webmd.com/vitamins/ai/ingredientmono-625/chitosan

2. https://jhpn.biomedcentral.com/articles/10.1186/s41043-025-00797-3

3. https://www.sciencedirect.com/science/article/abs/pii/S0144861796000331

4. https://www.webmd.com/vitamins-and-supplements/chitosan-uses-and-risks

5. https://www.medicinenet.com/chitosan_benefit_kidneys_are_there_side_effects/article.htm

6. https://www.rxlist.com/supplements/chitosan.htm#:~:text=Kidney%20failure.,are%20receiving%20long%2Dterm%20hemodialysis.

7. https://pmc.ncbi.nlm.nih.gov/articles/PMC6431530/#:~:text

8. https://www.verywellhealth.com/chitosan-everything-you-need-to-know-7866985

 

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