What Is Luteolin And How Is It Different From Quercetin?
May 06, 2025
What is Luteolin?
Luteolin extract is a natural flavonoid compound belonging to tetrahydroxyflavone, which has a typical antioxidant activity group. It is slightly soluble in water and easily soluble in organic solvents. If nano-encapsulation technology is used, the bioavailability can be improved.
Main natural sources:
| Sources | Representative species | Content (mg/100g) |
| Vegetables | Celery, green pepper, carrot | 10-50 |
| Herb | Chrysanthemum, rosemary, thyme | 50-200 |
| Fruit | Apple peels, citrus peels | 5-20 |
| Cereals | Buckwheat, sorghum | 15-30 |
health benefits of luteolin:
1. Antioxidant and anti-inflammatory
Best luteolin reduces chronic inflammation by removing reactive oxygen species and inhibiting the NF-κB pathway. Studies have found that it is better than salicylic acid in relieving colitis.
2. Neuroprotective
It can penetrate the blood-brain barrier and inhibit the aggregation of beta-amyloid protein. Animal studies have found that it can improve cognitive function.

3. Anti-allergic and immunomodulatory
It can block histamine H1 receptors and relieve hay fever symptoms.
4. Anti-tumor potential
Pure luteolin targets the PI3K/AKT pathway and inhibits breast cancer cell metastasis.
application:
1. Medicine and health products
- Anti-allergic drugs: It can be used with quercetin to relieve rhinitis.
- Neurodegenerative diseases: AD auxiliary treatment capsules.
2. Cosmetics
Use luteolin nanoliposomes to make cosmetics for better anti-aging.
3. Functional food
Luteolin powder can be added to anti-aging drinks.
Comparison of alternatives with similar functions:
| Product | Core differences | Application |
| Quercetin | Better water solubility, but weaker anti-inflammatory activity | Protect cardiovascular |
| Apigenin | Similar in structure, but poor in ability to penetrate the blood-brain barrier | Skin anti-allergy |
| Baicalin | Stronger antibacterial properties, but with a higher risk of hepatotoxicity | Adjunctive treatment of infectious diseases |
Contact Us:
Fruiterco is an export company that mainly produces plant extracts, health product raw materials, and cosmetic raw materials. The company has a 20+ professional service after-sales team.
Our products are sold to North America, Europe, Australia, South America and Asia. Our products have passed quality inspection and also support customer re-inspection. If you want to buy luteolin, you can contact us: Email: info@fruiterco.com.
References:
1.https://pmc.ncbi.nlm.nih.gov/articles/PMC2615542/
2. https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/luteolin
3. https://pmc.ncbi.nlm.nih.gov/articles/PMC4971424/
4. https://pmc.ncbi.nlm.nih.gov/articles/PMC6824624/
5. https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/luteolin
6. https://www.mdpi.com/2072-6643/16/12/1815
7. https://www.sciencedirect.com/topics/immunology-and-microbiology/luteolin
8. https://lutimax.com/blogs/news/foods-rich-in-luteolin-and-other-flavonoids
9. https://www.lifeextension.com/protocols/male-reproductive/male-hormone-restoration






