What Is The Difference Between Phosphatidylserine And Phosphatidylcholine?

 

PS Phosphatidylserine, abbreviated as PS in English, is a member of the phospholipid family. Phosphatidylserine participates in the transmission of nerve signals in the brain tissue of animals, and its content is the highest in the brain tissue.

 

Therefore, it is quite nutritious to stew fish head soup or buy some dry pot duck heads to eat when you are free. It is also found in soybeans. Now some health products containing phosphatidylserine are extracted from soybeans, and the effect is the same as that of mammalian sources.

 

• Structure: glycerol skeleton + two fatty acid chains + phosphoserine head group, the polar head contains serine residues (-CH₂-CH-COOH).
• Natural distribution: the inner layer of mammalian cell membrane (about 10-15%), and the content of neuronal cell membrane is as high as 20%.

 

 

1. Neurocognitive optimization

• Enhancement of synaptic plasticity: Promote dendritic branch growth by activating brain-derived neurotrophic factor (BDNF);
• Memory consolidation mechanism: Regulate NMDA receptor phosphorylation to improve long-term memory storage efficiency;
• Alzheimer's disease intervention: Reduce the deposition of amyloid-β plaques.

 

2. Stress and emotion regulation

• Cortisol balance: Inhibit over-activation of the hypothalamus-pituitary-adrenal axis and reduce stress cortisol peak by 40%;
• Anxiety relief: phosphatidylserine bulk increases GABA receptor sensitivity, and it is not addictive.

 

3. Improved athletic performance

• Anti-fatigue mechanism: Reduce lactic acid accumulation after exercise and accelerate its removal;
• Muscle repair: Promote satellite cell proliferation and shorten the period of delayed muscle soreness.

 

4. Cell life cycle management

• Apoptosis signal: Evert to the outer layer of the membrane as a "phagocytic signal" to guide macrophages to remove aging/diseased cells;
• Membrane stability maintenance: Maintain membrane fluidity by binding cholesterol and sphingomyelin.

 

 

PC phosphatidylcholine is structure is: glycerol skeleton + two fatty acid chains + phosphorylcholine head group, the polar head contains choline residues (-CH₂-CH₂-N⁺(CH₃)₃).

Natural distribution: outer layer of cell membrane, core component of alveolar surfactant.

 

 

Contrast	Phosphatidylserine powder	Phosphatidylcholine (PC)
Core metabolites	Serine, DHA	Choline, acetylcholine
Cognitive function	Enhance synaptic plasticity and inhibit excessive secretion of cortisol	Maintain myelin integrity and support nerve signal conduction speed
Lipid metabolism	Regulation of apolipoprotein A1	Promote VLDL synthesis
Apoptosis	Everting to the outer layer of the membrane as a "phagocytic signal"	Inhibits mitochondrial permeability transition pore
Natural food	Cow brain, squid	Egg yolk, soy lecithin
Synthesis process	Soybean Extract + Enzyme Conversion(≥ 50%)	Solvent extraction + supercritical purification (≥ 90%)
Common dosage forms	Soft capsules, sublingual fast-dissolving tablets	Granules, liposomes for injection

 

Used in combination with other products:

 

• PS+PC+Citicoline: Triple synergy to improve brain energy metabolism, used for post-stroke rehabilitation.
• PS+Ginkgo biloba extract: Improve microcirculation and delay the progression of vascular dementia.

 

 

Fruiterco is an export company that mainly produces plant extracts, health product raw materials, and cosmetic raw materials. The company has a 20+ professional service after-sales team.

 

Our products are sold to North America, Europe, Australia, South America and Asia. Our products have passed quality inspection and also support customer re-inspection. If you want to buy phosphatidylserine, you can contact us: Email: info@fruiterco.com.

 

 

1. https://my.clevelandclinic.org/health/drugs/25129-phosphatidylserine

2. https://www.webmd.com/vitamins/ai/ingredientmono-992/phosphatidylserine

3. https://www.canada.ca/en/health-canada/services/food-nutrition/public-involvement-partnerships/modification-list-permitted-supplemental-ingredients-enable-use-phosphatidylserine-soy/summary.html

4. https://www.verywellmind.com/the-benefits-of-phosphatidylserine-89496

5. https://www.rxlist.com/supplements/phosphatidylserine.htm

6. https://pubmed.ncbi.nlm.nih.gov/3338534/

7. https://examine.com/supplements/phosphatidylserine/?show_conditions=true

8. https://www.webmd.com/vitamins-and-supplements/phosphatidylserine-uses-and-risks

9. https://consensus.app/home/blog/what-is-phosphatidylserine-other-names-bc-ps-bovine-cortex-phosphatidylserine-fosfatidilserina/

10. https://www.medicinenet.com/phosphatidylcholine_benefits_side_effects/article.htm

11. https://bodybio.com/blogs/blog/phosphatidylserine-the-death-of-a-cell

12. https://bodybio.com/blogs/blog/pc-start-guide