Griffonia Simplicifolia Extract

 

Griffonia simplicifolia extract is a natural amino acid extracted from dried Ghana seeds. The main active ingredient is 5-hydroxytryptophan.

 

5-Hydroxytryptophan, the chemical name is 5-hydroxy-3-indolyl-α-aminopropionic acid, the English abbreviation is 5-HTP, and the molecular formula is C11H12N2O.

 

It is an organic compound with a light white-gray powder appearance. It is insoluble in water and soluble in methanol and ethanol. In addition, ghee seed extract is the main source of 5-hydroxytryptophan currently on the market.

 

 

Analysis	Specification	Result	Test method
Physical Description
Appearance	Off white fine powder	Off-white fine powder	Visual
Particle size	100% pass 80 mesh	100% pass 80 mesh	USP36<786>
Bulk density	20~60g/100ml	53.38g/100ml	Eur. Ph.7.0<2.9.34>
Tapped density	30~80g/100ml	72.38g/100ml	Eur. Ph.7.0<2.9.34>
Specific rotation	-34.7~-30.9˚	-32.8˚	Eur. Ph.7.0<2.9.13>
Solvent extract	Water & ethanol	Water & ethanol	/
Chemical Tests
Identification	Identical to R.S. sample	Identical	HPTLC
5-HTP (on dried basis)	98.0% Min	98.65%	HPLC
Loss on drying	1.0% Max	0.06%	Eur. Ph.7.0<2.5.12>
Ash	1.0% Max	0.38%	Eur. Ph.7.0<2.4.16>
Pesticides residue	Meet USP requirement	Complies	USP36<561>
Solvent residue	Meet Eur. Ph.7.0<5.4>	Complies	Meet Eur. Ph.7.0<2.4.24>
Heavy metals	10.0ppm Max	1.39ppm	Eur.Ph.7.0<2.2.58>ICP-MS
Lead (Pb)	1.0 ppm Max	0.063ppm	Eur.Ph.7.0<2.2.58>ICP-MS
Arsenic (As)	2.0 ppm Max	0.005ppm	Eur.Ph.7.0<2.2.58>ICP-MS
Cadmium (Cd)	1.0 ppm Max	0.005ppm	Eur.Ph.7.0<2.2.58>ICP-MS
Mercury (Hg)	3.0 ppm Max	0.025ppm	Eur.Ph.7.0<2.2.58>ICP-MS
Microbiology Control
Total plate count	1000cfu/g Max	<1000cfu/g	USP<2021>
Total Yeast & Mold	100cfu/g Max	<100cfu/g	USP<2021>
E. Coli	Negative	Negative	USP<2022>
Salmonella	Negative	Negative	USP<2022>
Conclusion	Complies with the USP standards.
General Status	Non-GMO, ISO Certificated.
Packing and Storage
Packing: Pack in paper-carton and two plastic-bags inside.
Shelf life: 2 year when properly stored.
Storage: Store in a well-closed place with constant low temperature and no direct sun light.

 

 

1. Treat insomnia
Griffonia seed extract is rich in 5-HTP. 5-HTP has a sedative effect that promotes sleep. Therefore, ghee seed extract is often used as a natural sleep promoter.

 

The 5-hydroxytryptophan contained in Ghanaian seed extract will produce serotonin in the human body, which is helpful for normal nerve and brain function. Serotonin can help sleep and effectively control pain. , can treat depression.

 

2. Analgesic effect
Griffonia simplicifolia extract may exert central analgesic effects by increasing 5-hydroxytryptamine (5-HT) content in the central nervous system. After the 5-HT descending fibers in the brain reach the spinal cord, they can be mediated by interneurons and activate enkephalin neurons in the dorsal glial area.

 

The latter can inhibit the transmission of peripheral pain information to the secondary level through presynaptic inhibition. neurons, thereby exerting central analgesic effects.

 

3. Effects on cardiovascular system
Research results show that TRP also has antihypertensive activity.

 

 

4. Hypnotic effect
Griffonia simplicifolia extract can use vitamin B6 to generate 5-hydroxytryptamine, the precursor of neurohormones, in the body, thereby promoting sleep and mental stability.

 

5. Regulate hormones
5-hydroxytryptophan can be converted into certain hormones to directly participate in endocrine activities, and it can also be converted into the central neurotransmitter 5-hydroxytryptamine to indirectly affect the release of neurohormones.

 

6. Lose weight
It can help suppress appetite by causing the body to consume fewer carbohydrates and by lowering stress hormones, which suppress appetite.

 

Shipping pictures, shipping country, shipping packaging

 

 

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