Polydeoxyribonucleotide PDRN

 

Polydeoxyribonucleotide PDRN was originally extracted primarily from salmon or trout sperm. With technological advancements, recombinant PDRN-produced via synthetic biology (such as microbial fermentation) or artificial synthesis-has also emerged.

 

Its key advantage lies in its 95%–98% similarity to human DNA, resulting in excellent biocompatibility and a low risk of triggering immune rejection. In the catalog of cosmetic ingredients, its INCI name is "Sodium DNA."

 

 

ITEMS	SPECIFICATIONS	RESULTS
Appearance	White to off-white powder or fibre polymer, particle	White powder
Identification	UV: Ratio of absorbance at 260nm and 280nm 1.8~2.0(max 258nm~262nm)	UV: Ratio of absorbance at 260nm and 280nm 1.9, max 258nm
Ph value	6.0~8.0	7.2
Loss on Drying	≤15.0%	7.23%
Heavy Metals	≤20ppm	Complies
Protein Content	≤2.0%	0.93%
Assay(UV)	≥90.0%	98.30%

 

 

1. Repair

Upon degradation, PDRN releases adenosine, which binds to A2A receptors on the cell surface and participates in anti-inflammatory processes, angiogenesis, and the regulation of fibroblast activity. This constitutes a key mechanism underlying its reparative effects, making it particularly suitable for post-aesthetic procedure recovery, as well as the healing of chronic ulcers and wounds.

 

2. Anti-aging

The nucleosides and nucleotides generated by Polydeoxyribonucleotide PDRN hydrolysis can be reused by cells as raw materials for DNA synthesis. They provide substrates for cellular repair and proliferation in damaged tissues, promote the synthesis of collagen and elastin, and inhibit MMP-1 expression, thereby improving fine lines and skin laxity; consequently, they are utilized in anti-aging creams and serums.

 

3. Anti-inflammatory

It regulates inflammatory cytokines such as TNF-α and IL-6 to reduce redness and swelling, making it suitable for sensitive skin care, rosacea treatment, and post-procedure inflammation control.

 

4. Brightening

PDRN upregulates VEGF to promote microcirculation and inhibit melanin production, thereby improving dullness and pigmentation; it is used in skin-brightening and "water-glow" (hydration/rejuvenation) treatments.

 

 

1. Medical Aesthetic Injection Combinations:

 

(1) Hyaluronic Acid: Formulated into a composite solution for injection into the facial dermis, achieving the dual effects of deep hydration and repair.

 

(2) Recombinant Type III Collagen: Combining this with hyaluronic acid significantly enhances absorption rates and stability; frequently used in premium "hydro-lifting" (skin-boosting) injections to promote fibroblast proliferation.

 

2. Combinations for daily skincare:

 

(1)Anti-aging and firming: Pair with peptides, copper peptides, and Pro-Xylane to enhance cellular activation and collagen regeneration.

 

(2) Soothing and redness reduction: Polydeoxyribonucleotide PDRN, combined with asiaticoside, bisabolol, and panthenol, delivers exceptional soothing and repairing benefits; it is especially suitable for sensitive skin.

 

(3) Brightening and radiance: Pair with glutathione, tranexamic acid, Vitamin C, and niacinamide to effectively address uneven skin tone and pigmentation issues.

 

 

Fruiterco is an export company that mainly produces plant extracts, health product raw materials, and cosmetic raw materials. The company has a 20+ professional service after-sales team.

 

Our products are sold to North America, Europe, Australia, South America and Asia. Our products have passed quality inspection and also support customer re-inspection.

 

 

 

Our company participated in the CPHI exhibition held in Barcelona, ​​Spain, from October 24 to 26, 2023 (Booth No.: 81C25). CPHI is an international exhibition focused on pharmaceutical ingredients, intermediates, finished formulations, and related sectors. It serves as a platform for the pharmaceutical and healthcare industries to showcase the latest products and technologies, expand business partnerships, and exchange industry insights.

 

To enhance our brand influence and demonstrate our capabilities to global clients, we made thorough preparations regarding our products, company profile, and services; consequently, a large number of customers visited our booth to inquire about our products.

 

 

 

Our products have obtained Organic, Halal, Kosher, HACCP, and USDA certifications. The company has also successfully passed ISO 22000 certification for food safety management systems. We are committed to providing our customers with high-quality products and support independent re-testing to ensure product quality.

 

 

 

We are a professional Polydeoxyribonucleotide PDRN Supplier; please feel free to contact us via email if you have any requirements for this product. Please contact us: Email: info@fruiterco.com.

 

 

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