Acetyl Tetrapeptide-15 Powder

 

Acetyl tetrapeptide-15 powder is a novel synthetic tetrapeptide that helps soothe sensitive skin by normalizing the tolerance threshold against environmental factors, certain irritating topical products, or skincare treatments. Mimicking natural opioid peptides, it is designed to reduce irritation of the skin's nerve endings.

 

Commonly used in sensitive skincare, Acetyl tetrapeptide-15 targets neuro-sensitive skin by inhibiting the release of pro-inflammatory mediators and boosting the skin's tolerance, thereby reducing reactivity, pain, and discomfort.

 

Its primary value in cosmetics can be summarized as follows:

 

• Soothes sensitive skin
• Helps reduce the skin's overreaction to external irritants
• Improves the sensory experience by alleviating discomfort such as stinging and burning sensations
• Suitable for sensitive skin care products
• Compatible with moisturizing and skin barrier-repairing ingredients
• Suitable for formulation development in post-procedure or skin-resurfacing product concepts

 

 

Items	Standards	Results
Appearance	White to off-white powder	Complies
Identity by ESI-MS	Theoretical MW: 613.7g/mol	Complies
Purity (HPLC)	≥98.0%	98.92%
Peptide Content(By N)	≥80.0%	85.97%
Water (K.F.)	≤7.0%	2.22%
Lead (mg/kg)	≤10	< 10
Arsenic (mg/kg)	≤2	< 2
Mercury (mg/kg)	≤1	< 1
Cadmium (mg/kg)	≤5	< 5
Total plate count (cfu/g)	≤1000	Complies
Yeast & mould (cfu/g)	≤100	Complies
Conclusion	Conforms to standard	Complies

 

 

1. Soothing Sensitive Skin

This is the primary application of Acetyl Tetrapeptide-15. Sensitive skin involves more than just thinness or a tendency to flush; symptoms can include stinging, burning, tightness, or general discomfort triggered by factors such as temperature changes, cosmetic ingredients, or friction.

Research into skincare products for sensitive skin indicates that Acetyl Tetrapeptide-15 is utilized in formulations designed for this skin type and is studied as a functional peptide with soothing properties.

 

2. Sensory Nerve Response

A distinctive feature of Acetyl Tetrapeptide-15 is that its primary focus is not merely on moisturization or antioxidation, but rather on modulating sensory nerve responses.

 

Research suggests that Acetyl tetrapeptide-15 powder influences signaling pathways associated with sensory nerve stimulation and involves mechanisms linked to the μ-opioid receptor. In vitro studies have demonstrated that the peptide can reduce the release of CGRP from sensory neurons under conditions of stimulation. Consequently, it is particularly well-suited for skincare formulations designed for skin prone to sensations of irritation, stinging, or discomfort.

 

3. Improving Skin Comfort

One of the product development concepts behind Acetyl Tetrapeptide-15 is to enhance the skin's tolerance to external irritants.

 

Small-scale human studies have evaluated formulations containing Acetyl Tetrapeptide-15 by observing sensory responses following capsaicin-induced irritation; reports indicate that the threshold of capsaicin stimulation required to trigger discomfort increased after use. Given the limited scale of these studies, the findings serve primarily to support the formulation concept and provide preliminary evidence of efficacy, rather than constituting conclusions drawn from large-scale clinical trials.

 

4. Convenient to store

The powder form is better suited for weighing, storage, purity control, and formulation development.

 

 

1. Skincare products for sensitive skin

This is the most direct application area; the ingredient can be incorporated into products such as serums and creams.

2. Formula Combination

Acetyl Tetrapeptide-15 is a small-molecule functional peptide that serves as a distinctive active ingredient in serums. It can be formulated in combination with ingredients such as:

• Panthenol
• Niacinamide
• Ceramides
• Hyaluronic Acid
• Beta-Glucan
• Allantoin
• Centella asiatica extract

 

3. Premium anti-sensitivity skincare products

In the premium skincare market, consumers are increasingly focused on issues such as sensitivity, stinging, redness, skin comfort, and the skin barrier. Compared to traditional botanical soothing ingredients, Acetyl Tetrapeptide-15 powder offers a more scientifically grounded peptide-based ingredient concept.

 

 

Fruiterco is an export company that mainly produces plant extracts, health product raw materials, and cosmetic raw materials. The company has a 20+ professional service after-sales team.

 

Our products are sold to North America, Europe, Australia, South America and Asia. Our products have passed quality inspection and also support customer re-inspection.

 

 

 

Our company participated in the CPHI exhibition held in Barcelona, ​​Spain, from October 24 to 26, 2023 (Booth No.: 81C25). CPHI is an international exhibition focused on pharmaceutical ingredients, intermediates, finished formulations, and related sectors. It serves as a platform for the pharmaceutical and healthcare industries to showcase the latest products and technologies, expand business partnerships, and exchange industry insights.

 

To enhance our brand influence and demonstrate our capabilities to global clients, we made thorough preparations regarding our products, company profile, and services; consequently, a large number of customers visited our booth to inquire about our products.

 

 

 

Our products have obtained Organic, Halal, Kosher, HACCP, and USDA certifications. The company has also successfully passed ISO 22000 certification for food safety management systems. We are committed to providing our customers with high-quality products and support independent re-testing to ensure product quality.

 

 

 

We are a professional Acetyl tetrapeptide-15 Powder Supplier; please feel free to contact us via email if you have any requirements for this product. Please contact us: Email: info@fruiterco.com.

 

 

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