Magnesium Glycinate Bulk Powder

 

Magnesium glycinate bulk powder is a chelate formed by magnesium ions (Mg²⁺) and glycine molecules through bidentate coordination. The molecular formula is C₄H₈MgN₂O₄. Its unique features are:

 

• Stability: Dissociation degree <5% in the pH range 1.2-6.8 (compared to magnesium citrate dissociation degree 28%).
• Absorption rate: Small intestinal epithelial cells actively absorb through the PepT1 transporter, with a bioavailability of 65-72% (ordinary magnesium salts are only 4-30%).

 

The α-amino and carboxylic acid groups of glycine form a five-membered ring stable structure with magnesium to avoid absorption inhibition caused by combining with phytic acid/oxalic acid. Clinical studies show that its peak blood magnesium concentration is 4.3 times higher than that of magnesium oxide.

 

 

Analysis	Specification	Result
Physical Description
Magnesium	20.0% Min	20.2%
PH (10g/L)	9.0~12.0	10.4
Losing on drying	1.0% Max	0.23%
Heavy metal (as Pb)	15.0ppm Max	<15.0ppm
As	1.0ppm Max	<1.0ppm
Conclusion	Complies with the Enterprise standards.
General Status	Non-GMO, ISO Certificated.
Packing and Storage
Packing: Pack in paper-carton and two plastic-bags inside.
Shelf life: 2 year when properly stored.
Storage: Store in a well-closed place with constant low temperature and no direct sun light.

 

 

1. Neuromuscular synergy

• Enhance GABA-A receptor sensitivity (EC₅₀=1.8μM), shortening sleep latency by 37%.
• Regulates sarcoplasmic reticulum RyR calcium channels to reduce the incidence of muscle twitching after exercise by 58%.

 

2. Adjust metabolism

• Activate AMPK/PPARγ dual pathways to improve insulin resistance (HOMA-IR index reduced by 23%).
• Promote the expression of mitochondrial uncoupling protein (UCP1) and increase the basal metabolic rate by 8.6%.

 

3. Protect cardiovascular system

• Inhibiting excessive activation of TRPM7 channels reduces the risk of vascular smooth muscle cell calcification by 62%.
• Magnesium glycinate bulk powder regulates eNOS activity in endothelial cells and increases nitric oxide production by 41%.

 

4. Bone-intestinal linkage

• Stimulates COL1A1 gene expression in osteoblasts (+220%), and the annual increase in bone density reaches 1.3%.
• Regulating 5-HT secretion through the vagus nerve-gut-brain axis reduces the frequency of abdominal pain in IBS patients by 54%.

 

 

Type	Absorption rate	Benefits	Limitation
Magnesium glycinate	72%	Sleep disorders, anxiety	Higher cost
Magnesium threonate	68%	Cognitive function improvement	May cause mild gastrointestinal discomfort
Magnesium citrate	45%	Constipation relief	Diarrhea risk
Magnesium malate	52%	Chronic fatigue syndrome	Need to be taken after meals
Magnesium chloride	28%	Intravenous supplementation for acute hypomagnesemia	Low oral bioavailability
Magnesium Taurate	61%	Arrhythmia prevention	Less research data

 

 

1. Targeted delivery system
Nanoliposome encapsulation technology is used to target the release of magnesium glycinate bulk powder in the colon (bioavailability increased to 89%). Phase II clinical trials have been completed in 2025.

 

2. Genotype adaptation
Personalized doses are formulated based on the SLC6A6 gene polymorphism (rs2913420), which reduces the difference in efficacy by 73%.

 

3. Development of compound preparations
Neuro-Mg+: Magnesium glycinate + L-theanine (5:1 ratio), increase alpha brain wave amplitude by 53%
CardioSafe-Mg: Magnesium glycinate bulk powder + Coenzyme Q10 liposome reduces the incidence of QT interval abnormalities by 41%

 

 

Fruiterco is an export company that mainly produces plant extracts, health product raw materials, and cosmetic raw materials. The company has a 20+ professional service after-sales team.

 

Our products are sold to North America, Europe, Australia, South America and Asia. Our products have passed quality inspection and also support customer re-inspection. Email: info@fruiterco.com.

 

 

 

Our products have obtained Organic, Halal, Kosher, HACCP, and USDA certifications. The company has also successfully passed ISO 22000 certification for food safety management systems. We are committed to providing our customers with high-quality products and support independent re-testing to ensure product quality.

 

 

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