Oleanolic Acid Benefits in Skin Care

 

Oleanolic acid powder is an organic acid widely found in nature. It was first obtained in China from Cinchona officinalis, a plant from the family Cinchonaaceae, for which it is named. Oleanolic acid can also be found in other plants, animals and microorganisms.

 

Oleanolic acid is a colorless crystalline solid that is soluble in water. It is an acidic substance with an acidic flavor.

 

Oleanolic acid has a variety of biological activities and applications. It is widely used in traditional Chinese medicine and is believed to have pharmacological effects such as anti-microbial, anti-oxidant, anti-inflammatory and anti-tumor.

 

Oleanolic acid is also used as a food additive, often as an acidifier and antioxidnt. In addition, oleanolic acid OA is used in the preparation of certain drugs and as a catalyst in the field of organic synthesis.

 

 

1. Liver protection
It can slow down the degeneration and necrosis of liver cells by lowering serum alanine aminotransferase activity and induce liver cell regeneration to repair necrotic tissues.

 

2. Anti-inflammatory
Oleanolic acid can also reduce serum globulin, which has a certain anti-inflammatory effect.

 

3. Nerve protection
Oleanolic acid can also inhibit the formation of pseudo-neurotransmitters, thus favoring the prevention and treatment of hepatic encephalopathy.

 

4. Hypoglycemia
Oleanolic acid(OA) significantly inhibited the increase in plasma glucose concentration. While oleanolic acid lowers blood glucose, both hepatic glycogen and serum insulin are significantly elevated.

 

It shows the effect of lowering blood glucose by inhibiting the transportation of sugar from the stomach to the small intestine and the transportation of sugar in the villi of the small intestine.

 

 

5. Anti-tumor
Oleanolic acid can act on different stages of tumorigenesis, including inhibiting tumor formation, hindering tumor induction and tumor cell differentiation. Oleanolic acid can also effectively inhibit angiogenesis, which in turn inhibits tumor cell invasion and metastasis.

 

6. Neuroprotective effects
A large number of experimental studies have found that oleanolic acid extract has a neuroprotective effect. Oleanolic acid has a protective effect on isolated nerve cell damage caused by neurotoxins such as B amyloid peptide, hydrogen peroxide, glutamate, 6-hydroxydopamine and so on.

 

7. Blood pressure reduction
Oleanolic acid can dilate blood vessels, reduce vascular resistance, normal and a variety of hypertensive animals have significant antihypertensive effect.

 

8. Antibacterial
Oleanolic acid has the effect of anti-Aureus, hemolytic streptococcus, Escherichia coli, Fusarium dysenteriae, typhoid fever bacillus, of which the effect of anti-typhoid fever bacillus and Aureus is stronger than that of chloramphenicol.

 

9. Antiviral
Oleanolic acid has antiviral effect. It is found that OA can not only inhibit herpes simplex virus, hepatitis B virus, hepatitis C virus, but also inhibit the replication of human immunodeficiency virus HIV-1 by directly inhibiting HIV-1 protease activity.

 

 

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