What Is The Difference Between Dihydroquercetin And Quercetin?
Jun 12, 2025
What is Dihydroquercetin?
Dihydroquercetin powder is a natural flavonoid compound, mainly found in plants such as larch, grape seeds, and onions. It is a hydrogenated derivative of quercetin. It has excellent antioxidant and anti-inflammatory properties and is often used in health products and drug research.
dihydroquercetin benefits:
1. Powerful antioxidant
It can scavenge free radicals, reduce oxidative stress, protect cells from damage, and delay aging. It works in conjunction with vitamin C/E to enhance the antioxidant effect.
2. Vascular Protection
It can enhance the activity of nitric oxide, promote blood supply, and improve athletic endurance, and is especially beneficial for people who engage in long-distance running and cycling.
3. Protect the liver
It can reduce liver damage caused by alcohol or toxins and promote liver cell repair.
4. Anti-inflammatory and immune regulation
DHQ dihydroquercetin can inhibit pro-inflammatory factors and relieve chronic inflammation such as arthritis. It can reduce delayed onset muscle soreness and is especially useful for strength training or post-marathon recovery.
5. Skin health
It can inhibit UV damage, promote collagen synthesis, and is used in anti-aging skin care products.
Side effects and precautions:
1. Safety:
Generally well tolerated, but high doses can cause side effects.
2. Drug interactions:
When used with anticoagulants, it increases the risk of bleeding.
3. Special populations:
There is little safety data for pregnant and lactating women, so try to avoid using it.

Dihydroquercetin vs Quercetin:
| Contrast | Dihydroquercetin(DHQ) | Quercetin |
| Chemical structure | Hydrogenated form of quercetin without C2=C3 double bond | Contains C2=C3 double bond, and the structure is more unsaturated |
| Bioavailability | Higher, fat-soluble, easier to absorb | Low, often need to be combined with lipids or black pepper to improve absorption |
| Antioxidant | Stronger (increased stability after hydrogenation) | Weaker, but still acts as an antioxidant |
| Anti-inflammatory | Focus on inhibiting early inflammatory response | Effective on a wide range of inflammatory pathways |
| Source | Larch bark, grape seeds | Sophora Japonica, apples, onions, citrus fruits |
Summary and suggestions:
1. Choice basis:
If you are looking for high antioxidant or cardiovascular protection, DHQ may be better; quercetin powder is more suitable for daily dietary supplementation.
2. Dosage reference:
The common dose of DHQ is 50-200 mg/day, and quercetin is 500-1000 mg/day (needs to be taken in divided doses).
3. Consult professionals:
Especially for patients with chronic diseases or those who are taking medication, it is recommended to use it under the guidance of a doctor.
Contact Us:
Fruiterco is an export company that mainly produces plant extracts, health product raw materials, and cosmetic raw materials. The company has a 20+ professional service after-sales team. We have HACCP, HALAL, KOSHER, ISO22000 and other certificates.
Our products are sold to North America, Europe, Australia, South America. Our products have passed quality inspection and also support customer re-inspection. If you want to buy dihydroquercetin powder, you can contact us: Email: info@fruiterco.com.
References:
1. https://pmc.ncbi.nlm.nih.gov/articles/PMC8857648/
2. https://www.webmd.com/vitamins/ai/ingredientmono-294/quercetin
3. https://www.mdpi.com/1420-3049/28/19/6989
4. https://pubmed.ncbi.nlm.nih.gov/39384026/
5. https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/taxifolin
6. https://en.ametis.ru/files/ametis/files/2019/Key%20benefits%20of%20Dihydroquercetin%20brochure.pdf
7. https://link.springer.com/article/10.1134/S1070428024603297#:~:text
8. https://www.sciencedirect.com/science/article/pii/S0002916523021603






