Coleus Forskohlii Extract

 

Coleus forskohlii extract is a natural plant extract obtained from the root of Coleus forskohlii, also known as Plectranthus barbatus. It contains bioactive compounds that have multiple functions, including supporting weight management by enhancing fat metabolism and improving blood circulation.

 

In addition, it also plays an eye-protective role by relieving eye fatigue. In cosmetic formulations, it is often formulated as a skin conditioning agent in cosmetics to improve skin texture and vitality.

 

Active ingredients:

Its main active ingredient, forskolin, is considered one of the most potent natural adenylate cyclase activators. Its pharmacological action involves direct agonism of adenylate cyclase, leading to a significant increase in intracellular cyclic adenosine monophosphate (cAMP) levels. Elevated cAMP acts as a second messenger, regulating key cellular functions such as:

 

• Accelerated lipolysis
• Regulation of hormone synthesis
• Relaxation of vascular smooth muscle
• Enhanced mitochondrial energy metabolism

This molecular mechanism underpins its dual role in metabolic regulation and systemic physiological homeostasis.

 

 

Analysis	Specification	Result	Test method
Physical Description
Appearance	White fine power	Complies	Visual
Odor	Characteristic	Characteristic	Organoleptic
Particle size	100% pass 80 mesh	Complies	AOAC973.03
Extract Solvents	Ethanol	Complies	GC
Chemical Tests
Assay (Forskolin)	98.0% Min	98.32%	HPLC
Loss on Drying (5h at 105℃)	3.0% Max	1.07%	USP33
Sulpphated Ash	0.5% Max	0.03%	USP33
Heavy metals	10.0ppm Max	Complies	USP33
Arsenic(As)	0.5ppm Max	Complies	AAS
Lead (Pb)	0.2ppm Max	Complies	AAS
Mercury (Hg)	0.5ppm Max	Complies	AAS
Cadmium (Cd)	0.5ppm Max	Complies	AAS
Residual Solvents	0.05% Max	Complies	GC
Residual Pesticide	Negative	Complies	USP33
Microbiology Control
Total plate count	1,000cfu/g Max	100cfu/g	USP33
Yeast & Mold	100cfu/g Max	34cfu/g	USP33
E. Coli	Negative	Complies	USP33
Salmonella	Negative	Complies	USP33
Conclusion	Complies with the standards.
General Status	Non-GMO, Non-irradiation, ISO Certificated.
Packing and Storage
Packing: Pack in paper-carton and two plastic-bags inside.
Shelf life: 2 year when properly stored.
Storage: Store in a well-closed place with constant low temperature and no direct sun light.

 

 

1. Reduction of intraocular pressure
Studies have shown that forskolin has cyclic adenosine monophosphate-activating activity in vitro, and that it can lower intraocular pressure in normal rabbits or inhibit high intraocular pressure in water-loaded rabbits.

 

2. Anti-inflammatory
Coleus forskohlii extract can effectively alleviate airway inflammatory response in a rat asthma model, and the mechanism is related to the regulation of MAPK signaling pathway.

 

 

3. Reducing blood pressure
Coleus forskohlii active ingredient inhibits platelet aggregation in vitro.

 

4. Antiasthmatic and antispasmodic effects
Coleus forskohlii has a significant spasmolytic effect on histamine spasmodic airway smooth muscle.

 

5. Anti-tumor effects
Coleus forskohlii extract has significant antitumor activity, and its antitumor effects have been reported to be focused on forskolin.

 

6. Weight loss
The mechanism of Forskolin for fat loss is to activate the fat burning mechanism in the body to reduce excess body fat, which is the fastest way to burn fat and build muscle.

 

Forskolin improves cardiovascular activity and supports the activation of the fat-burning mechanism, restoring the body's normal fat distribution.

 

Shipping pictures, shipping country, shipping packaging

 

 

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Our products have obtained Organic, Halal, Kosher, HACCP, and USDA certifications. The company has also successfully passed ISO 22000 certification for food safety management systems. We are committed to providing our customers with high-quality products and support independent re-testing to ensure product quality.

 

 

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