Gymnema Leaf Extract

 

Gymnema sylvestre is a vine native to India, Africa and Australia that has been traditionally used in Ayurvedic medicine to regulate blood sugar and improve metabolic function. Gymnema leaf extracts are known for their ability to inhibit sugar absorption and lower blood sugar.

 

Active ingredient:

 

1. Triterpenoid saponins

• Gymnemic Acids: It is the core active ingredient of Gymnema sylvestre, which can block the intestinal absorption of glucose and inhibit sweet taste receptors.
• Gymnemasides: It has anti-inflammatory and anti-diabetic functions, and some studies have shown that it can promote the regeneration of pancreatic beta cells.

 

2. Proanthocyanidins
Gymnema sylvestre is a good antioxidant that can protect cells from oxidation and enhance insulin sensitivity. It can be used as a drug component for diabetes.

 

3. Flavonoids
Gymnema sylvestre also contains flavonoids such as quercetin and kaempferol, which have anti-inflammatory, antibacterial and vascular protective effects.

 

4. Polyphenols
The most common polyphenol component is catechins, which can assist in metabolic management by regulating intestinal flora and inhibiting fat accumulation.

 

5. Alkaloids
Such as Gymnemosides, although the content is low, may have a certain effect on the regulation of the nervous system.

 

 

Item	Specification	Test result
Appearance	Brown Yellow Powder	Conforms
Odor	Characteristic	Conforms
Taste	Characteristic	Conforms
Purity	99%	Conforms
Loss on Drying	≤5.0%	Conforms
Ash	≤5.0%	Conforms
Particle size	95% pass 80 mesh	Conforms
Allergens	None	Conforms
Chemical Control
Heavy metals	NMT 10ppm	Conforms
Arsenic	NMT 2ppm	Conforms
Lead	NMT 2ppm	Conforms
Cadmium	NMT 2ppm	Conforms
Mercury	NMT 2ppm	Conforms
Microbiological Control
Total Plate Count	10,000cfu/g Max	Conforms
Yeast & Mold	1,000cfu/g Max	Conforms
E.Coli	Negative	Negative
Salmonella	Negative	Negative

 

 

1. Hypoglycemic effect
Gymnema leaf extract has a mild effect on normal blood sugar, but when combined with glucose or sucrose, it can significantly inhibit the increase in blood sugar levels and significantly reduce the secretion of plasma insulin.

 

2. Regulate blood sugar
By inhibiting the activity of α-glucosidase, it can slow down the decomposition of carbohydrates, stimulate insulin secretion, and improve the blood sugar level of patients with type 2 diabetes.

 

3. Inhibit sugar absorption
Gymnema leaf extract gymnemic acid binds to intestinal sugar receptors, reduces the absorption rate of glucose and fructose, and is suitable for assisting in sugar control diet.

 

4. Weight management
By reducing the desire for sweets (taste regulation) and reducing the activity of fat synthase, it assists in the treatment of obesity.

 

 

 

5. Antioxidant and anti-aging
Gymnema leaf extract polyphenols and flavonoids can remove free radicals and delay cell aging. They are used for anti-inflammatory repair in skin care products.

 

6. Protect pancreatic islet function
Animal experiments have shown that Gymnema can reduce pancreatic β-cell apoptosis and delay the progression of diabetes.

 

7. Immunomodulatory effect
Gymnema extract exhibits activity on human neutrophils and has a good immunomodulatory effect.

 

8. Antibacterial effect
Gymnema leaf extract has an inhibitory effect on microorganisms such as bacteria and fungi, and different concentrations of natural saponins and purified saponins have obvious antibacterial effects.

 

9. Pesticide
Gymnema extract can effectively kill mosquito larvae that can transmit malaria and filariasis. It is a natural insecticide and has no toxic effect on the environment.

 

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