Gynostemma Leaf Extract

 

Gynostemma leaf extract is a product extracted using the dry rhizome of the cucurbitaceous plant gynostemma pentaphyllum as raw material. The main active ingredient is gynostemma pentaphyllum saponin.

 

The roots, stems, leaves, buds, and fruits of gynostemma pentaphyllum contain saponins. However, the content shows obvious differences, with the highest content in leaves, followed by fruits, and the lowest content in roots.

 

 

1. Gynostemma pentaphylla polysaccharide
The leaves and stems of gynostemma pentaphyllum contain glucose, fructose, oligosaccharides and galactose, among which gynostemma pentaphyllum polysaccharide has no toxic side effects.

 

2. Amino acids
Research has found that gynostemma leaf extract contains 18 kinds of amino acids, including 8 kinds of essential amino acids for human body. Studies have found that the contents of lysine, leucine, and valine are much higher than those of many fruits and vegetables.

 

3. Flavonoids
The total flavonoid content in gynostemma extract is 2%-5%. Currently, only more than 10 types of flavonoids have been reported, including Phytolactin, Rutin and Quercetin.

 

4. Trace elements
It is reported that there are as many as 23 trace elements in gynostemma pentaphyllum, including 13 trace elements and 5 macroelements necessary for the human body. The content of trace elements varies depending on the place of production, and it is also a resource worthy of development and utilization.

 

5. Other ingredients
Gynostemma leaf extract also contains other chemical components such as alkaloids, organic acids, vitamins, terpenes, phospholipids, proteins, etc.

 

 

Analysis	Specification	Result	Test method
Physical Description
Appearance	Light yellow powder	Light yellow powder	Visual
Odor & Taste	Strong and Characteristic	Strong and Characteristic	Organoleptic
Particle size	90% pass 120 mesh	90% pass 120 mesh	100 Mesh Screen
Chemical Tests
Identification	Must Positive	Positive	TLC
Assay (Gypenosides)	98.0% Min	98.3%	UV WS3-Z-006-93 (Z)
Loss on drying	5.0% Max	1.1%	GB/T5009.3-2003
Residue on Ignition	5.0% Max	2.1%	GB/T5009.4-2003
Heavy metals (as Pb)	10.0ppm Max	<10.0ppm	CP2005
Arsenic (As)	1.0ppm Max	<1.0ppm	GB/T 5009.11-2003
Lead (Pb)	1.0ppm Max	<1.0ppm	GB/T 5009.12-2003
Microbiology Control
Total plate count	1,000cfu/g Max	<1,000cfu/g	GB/T 4789.2-2003
Yeast & Mold	100cfu/g Max	<100cfu/g	GB/T 4789.15-2003
Coliform	Negative	Negative	GB/T 4789.3-2003
Salmonella	Negative	Negative	GB/T 4789.4-2003
aureus	Negative	Negative	GB/T 4789.10-2003
Conclusion	Complies with the standards.
General Status	Non-GMO, ISO Certificated.
Packing and Storage
Packing: Pack in paper-carton and two plastic-bags inside.
Shelf life: 2 year when properly stored.
Storage: Store in a well-closed place with constant low temperature and no direct sun light.

 

 

1. Regulate blood lipids
Gynostemma pentaphyllum extract can effectively prevent and treat hyperlipidemia and atherosclerosis. This effect of regulating blood lipids is related to inhibiting the production of free fatty acids by adipocytes and promoting the synthesis of neutral fats.

 

2. Anti-tumor
Gynostemma pentaphyllum has significant anti-tumor effects in vivo and in vitro. Its mechanism of action is to inhibit the growth and reproduction of tumor cells through direct cytotoxicity.

 

Gynostemma leaf extract can significantly inhibit the proliferation of liver cancer cells, melanoma tumor cells, lung cancer cells and cervical cancer cells cultured in vitro, while having no adverse effects on normal cell proliferation.

 

 

3. Lower blood sugar
Studies have found that gynostemma leaf extract can significantly control blood sugar elevation and reduce the symptoms of polydipsia, polyphagia, and polyuria in diabetes, and has been gradually used in clinical applications.

 

The study also found that gynostemma pentaphylla gynostemma pentaphyllum polysaccharide can significantly reduce the level of glucose in the blood by changing the activity of glucose metabolism enzymes, significantly reduce insulin resistance parameters, and increase liver glycogen concentration.

 

4. Anti-aging
Studies have found that the anti-aging effect of gynostemma pentaphyllum extract is mainly achieved by enhancing SOD activity in the blood while reducing free radical activity.

 

5. Antibacterial
Studies have shown that gynostemma leaf extract polysaccharides from plants and injecting them into the injured body, they can bind to receptors on the surface of pathogens and enter the cells, killing or engulfing diseased cells, effectively enhancing sterilization and Antibacterial effect.

 

6. Calming
In terms of application and research in traditional Chinese medicine and veterinary medicine, gynostemma pentaphyllum has a very significant sedative and tranquilizing effect, and has the effect of tonifying the kidneys and strengthening the spleen. At the same time, it has the ideal effect of nourishing qi and blood, and can effectively resist stress reactions.

 

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Our products have obtained Organic, Halal, Kosher, HACCP, and USDA certifications. The company has also successfully passed ISO 22000 certification for food safety management systems. We are committed to providing our customers with high-quality products and support independent re-testing to ensure product quality.

 

 

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