What Is The Difference Between Alpha Arbutin And Beta Arbutin?

Dec 05, 2024

What is arbutin?

 

Arbutin powder, also known as arbutin, is an ingredient extracted from bearberry leaves of the Rhododendron plant. It can prevent the production of melanin by inhibiting the activity of tyrosinase in the body, thereby reducing skin pigmentation and removing stains. and freckles. It also has bactericidal and anti-inflammatory effects and is used in cosmetics.

 

Arbutin is mainly divided into alpha arbutin and beta arbutin, alpha arbutin is much more expensive than beta arbutin, this is mainly because beta arbutin is obtained by chemical synthesis, while alpha arbutin can only be prepared by enzymatic synthesis (microbial fermentation).

 

Alpha arbutin is more soluble in water and resistant to high temperature than beta arbutin, has good photostability, has no cytotoxicity in safe doses, and inhibits the production of melanin 10-15 times stronger than beta arbutin, so alpha arbutin is generally used in high-grade whitening cosmetics.

 

Alpha arbutin VS. beta arbutin:

 

1. Whitening effect

It is able to inhibit the activity of tyrosinase, reduce the production of melanin, thereby reducing pigmentation and even skin tone. Alpha arbutin powder for skin whitening.

 

Beta arbutin also has a certain whitening effect, but its whitening effect is weaker than that of alpha arbutin.

 

2. Stability
Alpha arbutin has good stability in aqueous and oily matrices, and is not easily affected by light, heat and pH. Beta arbutin is more susceptible to breakdown and failure under some conditions.

 

3. Solubility
Alpha arbutin has a high solubility and can be dissolved in solvents such as water and ethanol. Beta arbutin has a relatively low solubility and is slightly worse than alpha arbutin.

 

4. CAS:

Alpha arbutin: 84380-01-8, MF: C12H16O7

Beta arbutin: 497-76-7, MF: C12H16O7

 

arbutin

 

5. Security
Alpha arbutin is considered a relatively safe whitening ingredient with low skin irritation and is suitable for people with different skin types.

 

Beta arbutin powder is also safe, but it may cause skin irritation or allergic reactions in some cases, especially when used in high concentrations or on sensitive skin.

 

6. Inhibit tyrosine
Studies have shown that alpha arbutin can inhibit tyrosinase activity at relatively low concentrations, and its inhibitory effect on tyrosinase is better than beta arbutin.

 

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