Is Agaricus Blazei Better Than Other Mushrooms In Anti-Cancer?

Apr 18, 2025

What is Agaricus blazei extract?

 

Agaricus blazei is a rare edible and medicinal fungus native to Brazil. Agaricus blazei extract is mainly separated from fruiting bodies or mycelium through water extraction, alcohol extraction or enzymatic hydrolysis. Its core ingredients include:

 

  • Polysaccharides: β-glucan, accounting for 10%~50% of dry weight
  • Triterpenoids
  • Nucleic acid derivatives: enhance cell repair ability
  • Dietary fiber and minerals: selenium and zinc, which help anti-oxidation and help intestinal health

 

Differences between Agaricus blazei and other Mushroom:

 

1. Differences in active ingredients

 

  • Ganoderma Lucidum Extract:

Main components include ganoderic acid and polysaccharides, and its primary effects include protecting the liver and nerves.

 

  • Shiitake mushrooms:

Rich in shiitake polysaccharides, mainly used for antiviral.

 

  • Cordyceps sinensis:

The main ingredients are cordycepin and adenosine, which can help the human body's energy metabolism and lungs and kidneys.

 

  • Agaricus blazei Murrill:

It contains approximately five times the β-glucan of Ganoderma lucidum, and possesses excellent anti-cancer properties, surpassing Ganoderma lucidum.

 

2. Different effects

 

  • Anti-cancer:

Agaricus blazei mushroom extract primarily inhibits tumor angiogenesis by activating macrophages and natural killer cells, thereby preventing cancer. Lingzhi extract, on the other hand, can induce apoptosis in cancer cells.

 

 

  • Metabolism Regulator:

Agaricus blazei Murrill contains a unique polysaccharide structure that is more potent than regular shiitake mushrooms in regulating blood sugar and lipids.

 

3. Growth environment and cost
Agaricus blazei needs to be cultivated in a high temperature and high humidity environment, and commercial production is difficult, so the cost is expensive; while ordinary mushrooms are mostly food ingredients, artificial cultivation is simple, and the cost is low.

 

agaricus blazei extract benefits:

 

1. Enhance immunity
Clinical studies have shown that the β-glucan of agaricus mushroom powder can enhance T cell activity and assist patients undergoing radiotherapy and chemotherapy to reduce the risk of leukopenia.

 

2. Metabolic Regulators
It lowers postprandial blood sugar by inhibiting α-glucosidase activity. It also promotes the conversion of cholesterol into bile acids, improving blood lipids.

 

3. Maintaining Intestinal Health
It promotes the proliferation of probiotics, reduces inflammation, and strengthens the intestinal barrier.

 

4. Antioxidant
Agaricus blazei murill extract contains superoxide dismutase analogs, which have the ability to scavenge free radicals 20 times that of vitamin C and have good anti-aging and antioxidant effects.

 

5. Protect the liver
Triterpenoid components inhibit the activation of hepatic stellate cells and reduce the risk of fibrosis in alcoholic and non-alcoholic fatty liver.

 

Contact Us:

 

Fruiterco is an export company that mainly produces plant extracts, health product raw materials, and cosmetic raw materials. The company has a 20+ professional service after-sales team.

 

Our products are sold to North America, Europe, Australia, South America and Asia. Our products have passed quality inspection and also support customer re-inspection. If you want to buy agaricus blazei extract, you can contact us: Email: info@fruiterco.com.

 

References:

 

1. https://pmc.ncbi.nlm.nih.gov/articles/PMC2249742/

2. https://www.rxlist.com/supplements/agaricus_mushroom.htm

3. https://www.webmd.com/vitamins/ai/ingredientmono-1165/agaricus-mushroom

4. https://pjmd.zu.edu.pk/volume-10-issue-1/therapeutic-value-of-medicinal-mushroom-agaricus-blazei-murill/

 

5. Colauto NB, Dias ES, Gimenes MA, da Eira AF. Genetic characterization of isolates of the basidiomycete Agaricus blazei by RAPD. Braz J Micobiol. 2002;33:131–3. [Google Scholar]

 

6. Wasser SP, Didukh MY, de Amazonas MAL, Nevo E, Stamets P, da Eira AF. Is a widely cultivated culinary-medicinal royal sun Agaricus (the Himematsutake Mushroom) indeed Agaricus blazei Murrill? Intern J of Med Mushrooms. 2002;4:267–90. [Google Scholar]

 

7. Lindequist U, Niedermeyer THJ, Jülich WD. The pharmacological potential of mushrooms. ECAM. 2005;2:285–99. doi: 10.1093/ecam/neh107. 

 

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