What Is The Difference Between Betulin And Betulinic Acid?

Dec 02, 2025

what is Betulin Powder?

 

Betulin powder is a natural pentacyclic triterpenoid compound widely found in plants such as birch, possessing various biological activities and applications.

 

  • Its main sources: Birch bark, the core source, containing up to 30% of its dry weight.
  • Other plants: Roots of Saussurea costus (Asteraceae), roots of Myrtaceae, etc.

 

Supercritical CO₂ extraction yields a purity of up to 99% as determined by HPLC.

 

betulin benefits:

 

1. Anti-tumor effects

It can induce apoptosis in cancer cells and inhibit their proliferation, showing significant effects, especially against cervical cancer, neuroblastoma, and ovarian cancer.

 

2. Auxiliary regulation of blood lipids

Animal experiments show that betulin may help lower cholesterol and triglyceride levels by inhibiting cholesterol synthesis-related enzymes, thus having a certain auxiliary regulatory effect on people with hyperlipidemia.

 

3. Anti-inflammatory

Birch bark extract betulin can inhibit pro-inflammatory factors, reduce inflammatory responses, and may have an auxiliary effect in improving certain inflammatory diseases.

 

4. Antiviral

It has an inhibitory effect on HIV, interfering with the viral maturation process.

 

5. Hair care

It reduces hair protein breakdown, promotes hair growth, and improves shine.

 

6. Liver protection

It alleviates alcoholic liver damage and enhances antioxidant capacity.

 

7. Skin health

Betulin is often used in skin care products and helps improve acne, promote wound healing, and enhance the skin barrier function.

 

betulin uses:

 

1. Pharmaceutical Industry

 

2. Cosmetics

Added to hair care products and anti-inflammatory skin care products.

 

3. Food Additive

Used as a functional ingredient in health foods for anti-oxidation and metabolism regulation.

 

What is the difference between betulinic acid and Betulin?

 

Contrast Betulin Betulinic acid powder
Molecular formula C₃₀H₅₀O₂ C₃₀H₄₈O₃
Functional Group -OH -COOH
Appearance White crystals powder Light yellow crystals powder
Melting point 256-258℃ 295-298℃
Solubility Soluble in ethanol and chloroform; slightly soluble in cold water Slightly soluble in water, readily soluble in pyridine and tetrahydrofuran
Uses Pharmaceutical intermediates,hair care products,food additives Anti-cancer, anti-inflammatory, neuroprotective

 

Contact Us:

 

Fruiterco can provide efficient and convenient delivery methods for the products that customers need. For example: air, sea, express, you can rest assured of product quality problems during transportation.

 

We have professional business staff to communicate with you about your product needs and understanding. We are a high-quality zinc citrate powder supplier in China.

 

There is a professional mailbox system, if you want to buy betulin powder,you can leave a message at any time, we will reply as soon as we see it. Contact us: Email: info@fruiterco.com.

 

References:

 

1. https://pmc.ncbi.nlm.nih.gov/articles/PMC6259842/

2. https://pubmed.ncbi.nlm.nih.gov/37509141/#:~:text=Betulin%20is%20a%20natural%20triterpene%20that%20has,*%20Diabetes%20*%20Oxidative%20stress%20*%20Inflammation

3. https://pmc.ncbi.nlm.nih.gov/articles/PMC10377123/

4. https://www.herbs2000.com/h_menu/betulin.htm

5. https://innomost.com/what-is-betuinno-betulin

6. Tolstikov G.A., Flekhter O.B., Shul'ts E.E., Baltina L.A., Tolstikov A.G. Betulin and its derivatives. Chemistry and biological activity. Khim. Interes. Ust. Razv. 2005;13:1–30.

7. Schulze H., Pieroh K. Zur Kenntnis des Betulins. Chem. Ber. 1922;55:2322–2346.

8. Davy G.S., Halsall T.G., Jones E.R.H., Meakins G.D. The chemistry of the triterpenes. Part X. The structures of some isomerisation products from betulin and betulinic acid. J. Chem. Soc. 1951:2702–2705.

 

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